同行评议人体研究
已在同行评议期刊发表的人体研究，包括随机对照试验、队列分析与临床试验中期数据。这是本站证据等级中可信度最高的一类。
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需注意：即使是 A 级人体研究，样本量与随访时长仍可能不足以支撑强结论。涉及企业发布的中期数据时，本站会在正文中另行标注。
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← 返回分级说明Among individuals with valid LSM and ever eligible for HCV treatment (HCV RNA detectable or ever received treatment), 72% (1106/1525) self‐reported hi…
Additionally, only 3 out of 12 participants currently identified the practical execution of ACP (item 4), with a prevailing belief amongst most partic…
A total of 223 patients with familial hemophagocytic lymphohistiocytosis (FHLH) were enrolled from 27 centers across 27 provinces, municipalities, or …
Stress‐kinase pathways can have beneficial or detrimental effects in adipose tissue depending on the kinase, cell type, and metabolic context [].；To i…
We distinguish chosen activity, compelled activity, and survival aging to clarify how similar forms of engagement may reflect different degrees of aut…
These models included (1) classic AD models driven by AβArc or Aβ42 overexpression, or induced by OA; (2) neuroinflammatory models induced by lipopoly…
As shown in , this resulted in a significant decline in viability to 55.3% ± 6.2% of control at 24 h (P < 0.01).；Time-course analysis revealed progres…
LVESPsim increased from 95 ± 7 mmHg at age 25 to 107 ± 8 mmHg at age 75.；Brachial SBP and cfPWV followed a similar trend, whilst brachial DBP decrease…
A lower percentage of Mi was linked to a higher risk of death and shorter survival, whereas higher FATi alone was not significantly associated with mo…
Considering the average of all ethnicities, the MAE values were below 0.3 for 11 signs, except for interocular and perioral lip wrinkles, which showed…
Most participants held a university degree (45.1%), followed by junior college qualifications (23.4%) and a high school education or below (20.2%); 11…
In contrast the characteristic lysine methylene resonance around 2.9 ppm, present in gelatin, was markedly reduced in GelMA, confirming that lysine re…
HHS 发布《关于使用特定多肽散装物质进行 503A 配制的执法裁量政策》草案（FR 2026-22192 / 91 FR 68526），对 BPC-157、TB-500、MOTS-c、Epitalon、Semax、KPV 六种多肽暂不执法，条件严苛且不覆盖 503B 与复方。
港股励晶太平洋（00575.HK）公告：旗下 Deep Longevity 的美国消费者远程医疗平台 Accrua Health 延至 2026 年第四季度推出，分三阶段，首发主打减重与长寿抗衰肽类药物，核心为 AI 生成的 BloodAge 报告。
Concerning the molecular substrate of OPHSCCs, imbalances in signal transduction pathways are implicated in their onset and progression.；Among them, t…
There were no significant differences in sex distribution between the groups (p = 0.240).；44.34 years, p < 0.001), while the T1DM group was characteri…
Nested model comparisons showed that incorporating these patterns significantly improved model fit across all 144 WM metrics—the mean ΔR2 was 0.1897 (…
A total of 141 participants were included in the final analysis, with a mean age of 74.8 ± 6.6 years; 77 (54.6%) were women.；According to the GLIM cri…
Gut Microbiome Analysis] After a rigorous quality check and preprocessing, which removed about 20% of the sequences, all sequences were normalized to …
A ViT model was fine-tuned on [Formula: see text] ROI-to-ROI connectivity matrices to perform three binary age group classifications (Young versus Old…
用 BMI、HbA1c、总胆固醇、ALT、eGFR、收缩压、白细胞计数七项指标做非参数排序，NHANES 1988–2018 显示健康分布显著恶化且集中在下尾；反事实分解显示约三分之一可归因于人口老龄化与族裔结构变化。
There was a non-significant tendency towards lower levels in men (179.1 ± 73.8 ng/mL) compared to women (193.1 ± 78.9 ng/mL, p = 0.060 by Mann–Whitney…
Genotyping of the hTERT-MNS16A variant was performed through polymerase chain reaction (PCR), while relative LTL was measured using real-time PCR.；For…
This issue is particularly acute because many fundamental studies still rely on T cells from, mostly, healthy young donors. ‖ 结论：As the immune system …