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    <description>长寿科技、生物医药、再生医学最新研究进展</description>
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    <title><![CDATA[人类能活多久？数据质量困局让答案成谜]]></title>
    <link>https://longbiosci.com/news/Human-Lifespan-Data-Quality-Challenge-2026.html</link>
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    <description><![CDATA[Fight Aging! 深度分析人类寿命数据的选择性偏差问题：百岁老人数据质量堪忧，蓝区传说和珍妮·卡尔芒记录可能均非真实，揭示了长寿研究领域长期被忽视的方法论危机。]]></description>
    <pubDate>Fri, 12 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[IFNAR1 缺失驱动帕金森病痴呆]]></title>
    <link>https://longbiosci.com/news/IFNAR1-Mitochondria-Parkinson-Dementia-2026.html</link>
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    <description><![CDATA[丹麦研究团队首次在体证明，I型干扰素受体1（IFNAR1）在神经元与星形胶质细胞中的缺失通过损害线粒体自噬与能量代谢，逐步驱动帕金森病痴呆（PDD）的发生，揭示了神经退行性病变中细胞特异性病理机制的关键差异。]]></description>
    <pubDate>Fri, 12 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[长寿公司 NewLimit 融资 4.35 亿美元：表观遗传重编程迈入临床时代]]></title>
    <link>https://longbiosci.com/news/NewLimit-435M-Epigenetic-Reprogramming-2026.html</link>
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    <description><![CDATA[长寿科技公司 NewLimit 宣布完成 4.35 亿美元 C 轮融资，由 Founders Fund 领投，计划于 2027 年启动表观遗传重编程疗法首次人体临床试验，肝脏衰老干预率先推进。]]></description>
    <pubDate>Fri, 12 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[Retro Biosciences 估值达18亿美元：3年从实验室到临床候选药物]]></title>
    <link>https://longbiosci.com/news/Retro-Biosciences-1.8B-Valuation-2026.html</link>
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    <description><![CDATA[长寿科技公司 Retro Biosciences 宣布新一轮融资初始关闭，估值达18亿美元。公司在短短3年内将 RTR242 从适应症筛选推进至首次人体给药，展现了超常规的研发速度。]]></description>
    <pubDate>Fri, 12 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[终身限时进食延长健康寿命：小鼠研究揭示性别特异性效应]]></title>
    <link>https://longbiosci.com/news/Time-Restricted-Feeding-Healthspan-NatureAging-2026.html</link>
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    <description><![CDATA[Nature Aging最新研究显示，终身限时进食（无热量限制）可延长非肥胖小鼠的健康寿命，且对衰老相关病理和寿命的影响存在显著的性别差异，为时间营养学提供了重要临床前证据。]]></description>
    <pubDate>Fri, 12 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[长寿公司 NewLimit 融资 4.35 亿美元：表观遗传重编程迈入临床时代]]></title>
    <link>https://longbiosci.com/news/NewLimit-435M-Epigenetic-Reprogramming-2026.html</link>
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    <pubDate>Fri, 12 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[Retro Biosciences 估值达18亿美元：3年从实验室到临床候选药物]]></title>
    <link>https://longbiosci.com/news/Retro-Biosciences-1.8B-Valuation-2026.html</link>
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    <pubDate>Fri, 12 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[终身限时进食延长健康寿命：小鼠研究揭示性别特异性效应]]></title>
    <link>https://longbiosci.com/news/Time-Restricted-Feeding-Healthspan-NatureAging-2026.html</link>
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    <description><![CDATA[终身限时进食可延长非肥胖小鼠健康寿命，影响存在显著性别差异。Nature Aging 2026年6月发表。]]></description>
    <pubDate>Fri, 12 Jun 2026 00:00:00 +0000</pubDate>
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    <title><![CDATA[IFNAR1 缺失驱动帕金森病痴呆：线粒体与神经能量代谢的细胞特异性病理]]></title>
    <link>https://longbiosci.com/news/IFNAR1-Mitochondria-Parkinson-Dementia-2026.html</link>
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    <description><![CDATA[丹麦团队首次在体阐明IFNAR1在神经元与星形胶质细胞中的缺失如何通过损害线粒体自噬驱动PDD发生。]]></description>
    <pubDate>Fri, 12 Jun 2026 00:00:00 +0000</pubDate>
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    <title><![CDATA[人类能活多久？数据质量困局让答案成谜]]></title>
    <link>https://longbiosci.com/news/Human-Lifespan-Data-Quality-Challenge-2026.html</link>
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    <description><![CDATA[百岁老人数据质量堪忧，蓝区传说和珍妮·卡尔芒记录可能均非真实，长寿研究领域面临方法论危机。Fight Aging! 2026年6月分析。]]></description>
    <pubDate>Fri, 12 Jun 2026 00:00:00 +0000</pubDate>
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    <title><![CDATA[磷脂酰胆碱流失：细胞衰老的]]></title>
    <link>https://longbiosci.com/news/Phosphatidylcholine-Mitochondrial-Aging-Nature-Communications-2026.html</link>
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    <description><![CDATA[德国莱布尼茨衰老研究所（FLI）团队在Nature Communications发表研究：随年龄增长的磷脂酰胆碱水平下降是线粒体功能障碍的重要驱动因素。补充磷脂酰胆碱或胆碱，可在仅两天内恢复线粒体年轻态，提示生物衰老具有可逆性。]]></description>
    <pubDate>Thu, 11 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[磷脂酰胆碱流失：细胞衰老的]]></title>
    <link>https://longbiosci.com/news/Phosphatidylcholine-Mitochondrial-Aging-Nature-Communications-2026.html</link>
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    <description><![CDATA[德国FLI研究团队在Nature Communications发表研究，揭示磷脂酰胆碱流失是线粒体衰老的关键驱动因素，补充该物质可在两天内恢复线粒体年轻态。]]></description>
    <pubDate>Thu, 11 Jun 2026 00:00:00 +0000</pubDate>
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    <title><![CDATA[工程菌群替代粪菌移植：15菌株LBP临床试验证明等效性]]></title>
    <link>https://longbiosci.com/news/Engineered-Gut-Bacteria-LBP-FMT-Clinical-Trial-2026.html</link>
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    <description><![CDATA[加州大学圣地亚哥分校团队开发出标准化工程菌群（LBP），在复发性艰难梭菌感染临床试验中与粪菌移植（FMT）达到等效，为规模化肠道菌群疗法奠定基础，也为抗衰老肠道干预带来新希望。]]></description>
    <pubDate>Wed, 10 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[线粒体：衰老的主调控器，连接能量代谢与慢性炎症]]></title>
    <link>https://longbiosci.com/news/Mitochondria-Master-Regulator-Aging-Inflammaging-2026.html</link>
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    <description><![CDATA[2026年6月开放获取综述提出线粒体功能障碍不仅是衰老的标志之一，更是干细胞耗竭与炎症衰老的 upstream 上游驱动因素，整合生物能量学、氧化还原调控与固有免疫信号，为抗衰老干预提供系统性框架。]]></description>
    <pubDate>Wed, 10 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[cGAS-STING通路与神经炎症：从感知机制到治疗靶点]]></title>
    <link>https://longbiosci.com/news/cGAS-STING-Neuroinflammation-Therapeutic-Target-2026.html</link>
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    <description><![CDATA[2026年6月开放获取综述深入解析cGAS-STING信号通路在衰老大脑中的过度激活如何驱动神经炎症与神经退行，并探讨选择性抑制该通路作为神经退行性疾病治疗策略的可行性。]]></description>
    <pubDate>Wed, 10 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[cGAS-STING通路与神经炎症：从感知机制到治疗靶点 - LongBiosci]]></title>
    <link>https://longbiosci.com/news/cGAS-STING-Neuroinflammation-Therapeutic-Target-2026.html</link>
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    <description><![CDATA[2026年6月开放获取综述深入解析cGAS-STING信号通路在衰老大脑中的过度激活如何驱动神经炎症与神经退行，并探讨选择性抑制该通路作为神经退行性疾病治疗策略的可行性。]]></description>
    <pubDate>Wed, 10 Jun 2026 00:00:00 +0000</pubDate>
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    <title><![CDATA[线粒体：衰老的主调控器，连接能量代谢与慢性炎症 - LongBiosci]]></title>
    <link>https://longbiosci.com/news/Mitochondria-Master-Regulator-Aging-Inflammaging-2026.html</link>
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    <description><![CDATA[2026年6月开放获取综述提出线粒体功能障碍不仅是衰老的标志之一，更是干细胞耗竭与炎症衰老的 upstream 上游驱动因素，整合生物能量学、氧化还原调控与固有免疫信号，为抗衰老干预提供系统性框架。]]></description>
    <pubDate>Wed, 10 Jun 2026 00:00:00 +0000</pubDate>
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    <title><![CDATA[工程菌群替代粪菌移植：15菌株LBP临床试验证明等效性]]></title>
    <link>https://longbiosci.com/news/Engineered-Gut-Bacteria-LBP-FMT-Clinical-Trial-2026.html</link>
    <guid isPermaLink="true">https://longbiosci.com/news/Engineered-Gut-Bacteria-LBP-FMT-Clinical-Trial-2026.html</guid>
    <description><![CDATA[标准化工程菌群在复发性艰难梭菌感染试验中与FMT等效，为规模化肠道疗法奠定基础。]]></description>
    <pubDate>Wed, 10 Jun 2026 00:00:00 +0000</pubDate>
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    <title><![CDATA[错位核酸触发凝血衰老：Ageing Research Reviews 2026 综述解读]]></title>
    <link>https://longbiosci.com/news/Misplaced-Nucleic-Acids-Coagul-Aging-2026.html</link>
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    <description><![CDATA[Ageing Research Reviews 2026发表重磅综述：细胞内错位DNA/RNA片段通过cGAS-STING等模式识别受体，同时触发慢性炎症和凝血级联反应，提出\]]></description>
    <pubDate>Tue, 09 Jun 2026 12:00:00 GMT</pubDate>
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    <title><![CDATA[限时进食延长健康寿命：终生实验揭示性别差异]]></title>
    <link>https://longbiosci.com/news/Time-Restricted-Feeding-Healthspan-Lifespan-NatureAging-2026.html</link>
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    <description><![CDATA[Iiams等人终生小鼠实验证明，限时进食（TRF）在不改变饮食热量的情况下显著延长健康寿命，且存在显著性别差异：雄性小鼠寿命延长，雌性小鼠虽寿命未显著增加但健康寿命指标全面改善。这一发现将]]></description>
    <pubDate>Tue, 09 Jun 2026 12:00:00 GMT</pubDate>
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