https://longbiosci.com 最新生物医药与长寿科技研究资讯 zh-cn Wed, 04 Nov 2026 21:51:36 GMT https://longbiosci.com/news/The-independent-and-joint-impact-social-and-internet-isolation-2026.htmlhttps://longbiosci.com/news/The-independent-and-joint-impact-social-and-internet-isolation-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部OBJECTIVES: This study examined independent and joint associations of social and internet isolation with incident depression and loneliness among older adults in two culturally distinct coho https://longbiosci.com/news/The-healthcare-cost-multimorbidity-older-patients-with-atrial-fibrillation-2026.htmlhttps://longbiosci.com/news/The-healthcare-cost-multimorbidity-older-patients-with-atrial-fibrillation-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Atrial fibrillation (AF) in older adults often coexists with comorbidities, increasing healthcare costs. Understanding the economic impact of different comorbidity patterns is es https://longbiosci.com/news/The-gut-microbiome-immunotherapy-lessons-learned-from-melanoma-and-2026.htmlhttps://longbiosci.com/news/The-gut-microbiome-immunotherapy-lessons-learned-from-melanoma-and-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部RELEVANCE: Immune checkpoint blockade has revolutionized the therapeutic landscape in both hematology and oncology. Critically, persistent remissions are achieved in up to 50 % of patients. https://longbiosci.com/news/The-gut-brain-vascular-axis-converging-neuroinflammatory-and-hypertension-mediated-pathways-from-2026.htmlhttps://longbiosci.com/news/The-gut-brain-vascular-axis-converging-neuroinflammatory-and-hypertension-mediated-pathways-from-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部The gut harbors approximately 38 trillion microorganisms (3) that collectively produce thousands of bioactive metabolites, modulate host immune function, regulate autonomic tone, and maintai https://longbiosci.com/news/The-efficacy-and-safety-lurasidone-adolescents-with-bipolar-disorder-2026.htmlhttps://longbiosci.com/news/The-efficacy-and-safety-lurasidone-adolescents-with-bipolar-disorder-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部INTRODUCTION: Bipolar disorder (BD) is a psychiatric condition characterized by recurrent episodes of mania or hypomania and depression, impairing psychosocial functioning across-the-lifespa https://longbiosci.com/news/The-cup-on-cup-technique-for-managing-massive-acetabular-defects-revision-2026.htmlhttps://longbiosci.com/news/The-cup-on-cup-technique-for-managing-massive-acetabular-defects-revision-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部The use of the Harris Hip Score (HHS) demonstrated that, in selected patients, it is possible to obtain excellent post-operative scores, close to normal.；In summary, the set of these assessm https://longbiosci.com/news/The-Structural-and-Biochemical-Organization-Myelin-Health-and-Pathology-2026.htmlhttps://longbiosci.com/news/The-Structural-and-Biochemical-Organization-Myelin-Health-and-Pathology-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部This review examines current understanding of myelin biology and its adaptive roles in health, disease, and aging. We describe the cell populations involved in myelination, demyelination, an https://longbiosci.com/news/The-Royal-College-Ophthalmologists-National-Ophthalmology-Database-report-severe-2026.htmlhttps://longbiosci.com/news/The-Royal-College-Ophthalmologists-National-Ophthalmology-Database-report-severe-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND/OBJECTIVES: To investigate rates of severe vision loss post-cataract surgery. SUBJECTS/METHODS: Post-cataract severe vision loss (SVL) was defined as a loss of ≥0.60 LogMAR betwee https://longbiosci.com/news/The-Role-miRNAs-Regulating-Cellular-Senescence-A-Potential-Strategy-2026.htmlhttps://longbiosci.com/news/The-Role-miRNAs-Regulating-Cellular-Senescence-A-Potential-Strategy-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to late diagnosis and the frequent development of resistance to platinum-based chemotherapy and taxanes. https://longbiosci.com/news/The-Role-Drosophila-Toll-Receptors-the-Central-Nervous-System-2026.htmlhttps://longbiosci.com/news/The-Role-Drosophila-Toll-Receptors-the-Central-Nervous-System-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Toll-like receptors (TLRs) are evolutionarily conserved pattern recognition receptors that play pivotal roles in innate immunity by detecting pathogen-associated molecular patterns. While in https://longbiosci.com/news/The-Relationships-Among-Joy-Life-Social-Support-and-Life-2026.htmlhttps://longbiosci.com/news/The-Relationships-Among-Joy-Life-Social-Support-and-Life-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部AIM: This study aims to examine the multidimensional nature of well-being in old age by investigating the structural interrelations among joy of life, psychological well-being, and life sati https://longbiosci.com/news/The-Potential-Role-Gut-Microbiome-Dysbiosis-and-Functional-Reprogramming-2026.htmlhttps://longbiosci.com/news/The-Potential-Role-Gut-Microbiome-Dysbiosis-and-Functional-Reprogramming-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Colorectal liver metastasis (CRLM) is a leading cause of mortality in colorectal cancer (CRC), yet current surveillance often misses occult micrometastases, underscoring an urgen https://longbiosci.com/news/The-National-Couples-Health-and-Time-Stress-Biology-Study-2026.htmlhttps://longbiosci.com/news/The-National-Couples-Health-and-Time-Stress-Biology-Study-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部OBJECTIVE: Sexual minority populations are growing, experience elevated physical and mental health risks, and have unique stressor exposures. However, biopsychosocial research on sexual mino https://longbiosci.com/news/The-Korean-Frailty-and-Aging-Cohort-Study-A-Decade-2026.htmlhttps://longbiosci.com/news/The-Korean-Frailty-and-Aging-Cohort-Study-A-Decade-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部These results demonstrate that it is important to identify risk factors early and implement appropriate preventive management before frailty worsens, showing the potential to prevent or dela https://longbiosci.com/news/The-Impact-Age-and-Presentation-with-Vision-Loss-Pituitary-2026.htmlhttps://longbiosci.com/news/The-Impact-Age-and-Presentation-with-Vision-Loss-Pituitary-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部OBJECTIVE: In this single-center study, we aimed to determine if age at presentation was associated with vision loss and if this effect could be explained by tumor volume and/or cavernous si https://longbiosci.com/news/The-Hypothalamic-Paraventricular-Nucleus-Integrative-Hub-Circadian-Regulation-and-2026.htmlhttps://longbiosci.com/news/The-Hypothalamic-Paraventricular-Nucleus-Integrative-Hub-Circadian-Regulation-and-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Circadian rhythms are endogenous, approximately 24-hour oscillations that align physiology and behavior with the environmental light-dark cycle and support homeostasis. In mammals, the supra https://longbiosci.com/news/The-Gut-Brain-Homeostatic-Continuum-Alzheimer-disease-systems-framework-for-2026.htmlhttps://longbiosci.com/news/The-Gut-Brain-Homeostatic-Continuum-Alzheimer-disease-systems-framework-for-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部These observations suggest that cerebral pathology alone may not be sufficient to fully explain individual differences in disease susceptibility, progression and clinical expression.This dis https://longbiosci.com/news/The-FOXA2-BNIP3-axis-alleviates-acute-necrotizing-pancreatitis-promoting-mitophagy-2026.htmlhttps://longbiosci.com/news/The-FOXA2-BNIP3-axis-alleviates-acute-necrotizing-pancreatitis-promoting-mitophagy-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Acute necrotizing pancreatitis (ANP) is a severe inflammatory pancreatic disease characterized by pancreatic necrosis and systemic inflammation, with complex pathogenesis, rapid progression, https://longbiosci.com/news/The-FOX-Family-Key-Regulators-Aging-Related-Pathways-2026.htmlhttps://longbiosci.com/news/The-FOX-Family-Key-Regulators-Aging-Related-Pathways-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部The Forkhead box (FOX) family comprises a group of transcription factors distinguished by a wing-like helix structure in their DNA-binding domain and encompasses 19 subfamilies, including Fo https://longbiosci.com/news/The-FDA-Approved-and-Non-FDA-Approved-Indications-for-Biostimulatory-Fillers-off-2026.htmlhttps://longbiosci.com/news/The-FDA-Approved-and-Non-FDA-Approved-Indications-for-Biostimulatory-Fillers-off-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Biostimulatory fillers are increasingly used beyond the face to address age-related dermal thinning, laxity, crepiness, and soft-tissue volume loss through neocollagenesis and ti https://longbiosci.com/news/The-Elastotic-Hemangioma-the-Vulva-Nodular-Vulvar-Elastosis-With-2026.htmlhttps://longbiosci.com/news/The-Elastotic-Hemangioma-the-Vulva-Nodular-Vulvar-Elastosis-With-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Acquired elastotic hemangioma is an uncommon benign cutaneous vascular proliferation first described in 2002 that typically presents as a solitary erythematous plaque arising on chronically https://longbiosci.com/news/The-AMPK-ALDH7A1-axis-drives-metabolic-reprogramming-and-anti-tumor-immunity-2026.htmlhttps://longbiosci.com/news/The-AMPK-ALDH7A1-axis-drives-metabolic-reprogramming-and-anti-tumor-immunity-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Mitochondrial dysfunction is a feature of hepatocellular carcinoma (HCC), yet how respiratory suppression arises remains unclear. Here, we identify an evolutionarily conserved metabolic-epig https://longbiosci.com/news/Tetrahydroberberine-Suppresses-Autophagy-and-Mitigates-Doxorubicin-Induced-Ferroptosis-Hepatic-Cells-2026.htmlhttps://longbiosci.com/news/Tetrahydroberberine-Suppresses-Autophagy-and-Mitigates-Doxorubicin-Induced-Ferroptosis-Hepatic-Cells-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部This study investigated the hepatoprotective mechanism of tetrahydroberberine (THB) against doxorubicin (DOX)-induced liver injury. Using DOX-induced drug-induced liver injury (DILI) mouse m https://longbiosci.com/news/Temporal-Trends-the-Prevalence-Frailty-England-From-2002-2022-2026.htmlhttps://longbiosci.com/news/Temporal-Trends-the-Prevalence-Frailty-England-From-2002-2022-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: The increasing life expectancy provides an opportunity for healthy longevity, but frailty is a potential challenge. Existing studies of frailty prevalence in England are largely https://longbiosci.com/news/Telomere-to-telomere-genome-assembly-the-endangered-Jacktree-Sinojackia-xylocarpa-reveals-2026.htmlhttps://longbiosci.com/news/Telomere-to-telomere-genome-assembly-the-endangered-Jacktree-Sinojackia-xylocarpa-reveals-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部The endangered status of many plant species is often attributed to a decline in fitness, which drives a sustained decrease in population size under natural conditions. However, the role of h https://longbiosci.com/news/Telomere-length-systemic-aging-related-susceptibility-marker-for-trigeminal-neuralgia-2026.htmlhttps://longbiosci.com/news/Telomere-length-systemic-aging-related-susceptibility-marker-for-trigeminal-neuralgia-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部ObjectiveTo evaluate whether genetically proxied leukocyte telomere length (TL), a systemic marker of biological aging and cumulative cellular stress, is associated with trigeminal neuralgia https://longbiosci.com/news/Tea-polyphenols-the-sensory-functional-interface-Bitterness-astringency-bioactivity-and-2026.htmlhttps://longbiosci.com/news/Tea-polyphenols-the-sensory-functional-interface-Bitterness-astringency-bioactivity-and-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Tea polyphenols, especially catechins, contribute to bitterness and astringency while also being widely investigated for potential health-related bioactivities. This sensory-functional tensi https://longbiosci.com/news/Task-Related-Differences-Lip-Motor-Performance-Between-Children-and-Adults-2026.htmlhttps://longbiosci.com/news/Task-Related-Differences-Lip-Motor-Performance-Between-Children-and-Adults-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Objective assessments of lip-closing function in children are increasingly of interest, but the task-specific, age-related characteristics of lip motor coordination remain unclea https://longbiosci.com/news/Targeting-the-immunity-cell-death-axis-multi-parametric-network-approach-traditional-2026.htmlhttps://longbiosci.com/news/Targeting-the-immunity-cell-death-axis-multi-parametric-network-approach-traditional-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Collectively, these events activate programmed cell death (PCD) pathways, culminating in the “secondary insult” that defines renal tissue damage.；Notably, different forms of PCD do not exist https://longbiosci.com/news/Targeting-carbonic-anhydrase-IX-overcome-hypoxia-driven-resistance-glioblastoma-2026.htmlhttps://longbiosci.com/news/Targeting-carbonic-anhydrase-IX-overcome-hypoxia-driven-resistance-glioblastoma-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Glioblastoma multiforme (GBM) is the most aggressive primary brain tumour in adults, with a median overall survival of approximately 15 months despite multimodal treatment. Tumour hypoxia, a https://longbiosci.com/news/Targeting-Nur77-Fibrosis-and-Aging-Context--and-Stage-Specific-Molecular-2026.htmlhttps://longbiosci.com/news/Targeting-Nur77-Fibrosis-and-Aging-Context--and-Stage-Specific-Molecular-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Fibrosis represents the end-stage manifestation of numerous chronic diseases, characterized by persistent inflammatory cell infiltration, fibroblast-to-myofibroblast transition, and excessiv https://longbiosci.com/news/Targeting-N-acetyltransferase-reprograms-Treg-function-enhance-anti-PD-1-immunotherapy-sensitivity-2026.htmlhttps://longbiosci.com/news/Targeting-N-acetyltransferase-reprograms-Treg-function-enhance-anti-PD-1-immunotherapy-sensitivity-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部IntroductionIncreasing evidence indicates that elevated frequencies of tumor-infiltrating (TI) Tregs correlate with poor prognosis in patients with cancer.；Notably, functionally heterogeneou https://longbiosci.com/news/Targeting-Endoplasmic-Reticulum-Stress-Promising-Strategy-Against-Aging-2026.htmlhttps://longbiosci.com/news/Targeting-Endoplasmic-Reticulum-Stress-Promising-Strategy-Against-Aging-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部The endoplasmic reticulum (ER) is a vital organelle in eukaryotic cells that plays a key role in processes such as protein folding, post-translational modifications, and the regulation of in https://longbiosci.com/news/Targeting-Accelerated-Aging-COPD-The-AMICO-A-Trial-Metformin-2026.htmlhttps://longbiosci.com/news/Targeting-Accelerated-Aging-COPD-The-AMICO-A-Trial-Metformin-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is increasingly recognized as a disease of accelerated biological aging characterized by progressive lung function decline, emphyse https://longbiosci.com/news/TM9SF1-Promotes-YAP-Mediated-EMT-Alveolar-Epithelial-Cells-VILI-Enhancing-2026.htmlhttps://longbiosci.com/news/TM9SF1-Promotes-YAP-Mediated-EMT-Alveolar-Epithelial-Cells-VILI-Enhancing-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Our data demonstrated that TM9SF1 promoted autophagic degradation of CLDN18, leading to YAP activation and subsequent EMT, and identified the TM9SF1‐CLDN18‐YAP axis as a potential therapeuti https://longbiosci.com/news/TERRA-induced-responder-telomere-dysfunction-2026.htmlhttps://longbiosci.com/news/TERRA-induced-responder-telomere-dysfunction-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Telomeric repeat-containing RNA (TERRA) has long been viewed as a constitutive component of telomeres. However, accumulating experimental evidence suggests that TERRA is instead a stress-res https://longbiosci.com/news/TEMPORARY-REMOVAL-Between-Care-and-Influence-Relational-Autonomy-the-2026.htmlhttps://longbiosci.com/news/TEMPORARY-REMOVAL-Between-Care-and-Influence-Relational-Autonomy-the-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部The publisher has temporarily withdrawn the above article, which was published online prematurely because of a technical error in our production system. The article is accepted for publicati https://longbiosci.com/news/T2D-inadequately-controlled-with-metformin-orforglipron-reduced-HbA-more-2026.htmlhttps://longbiosci.com/news/T2D-inadequately-controlled-with-metformin-orforglipron-reduced-HbA-more-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部GIM/FP/GP: [Formula: see text] Endocrinology: [Formula: see text]. https://longbiosci.com/news/Systematic-Review-and-Meta-Analysis-the-Transitions-Trajectories-and-Associations-2026.htmlhttps://longbiosci.com/news/Systematic-Review-and-Meta-Analysis-the-Transitions-Trajectories-and-Associations-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部However, these findings are not generalizable to community‐dwelling adults.；Overall, frailty was consistently associated with higher mortality risks.；These findings indicate that both absolu https://longbiosci.com/news/Sympathetic-Regulation-Bone-Metabolism-Mechanisms-across-Homeostasis-Aging-and-2026.htmlhttps://longbiosci.com/news/Sympathetic-Regulation-Bone-Metabolism-Mechanisms-across-Homeostasis-Aging-and-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部First, causal effects demonstrated in genetic, pharmacological, or denervation models establish mechanism within the tested species, skeletal site, disease model, dose, and time window, but https://longbiosci.com/news/Surface-morphology-printing-accuracy-and-flexural-strength-3D-printed-zirconia-2026.htmlhttps://longbiosci.com/news/Surface-morphology-printing-accuracy-and-flexural-strength-3D-printed-zirconia-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部ACJ-fabricated zirconia restorations exhibit greater geometric precision and demonstrate technical feasibility in manufacturing customized morphological features [10].；These findings support https://longbiosci.com/news/Structure-Guided-Remodeling-Multi-Substrate-Binding-Pocket-Nicotinamide-Mononucleotide-Adenylyltransferase-for-2026.htmlhttps://longbiosci.com/news/Structure-Guided-Remodeling-Multi-Substrate-Binding-Pocket-Nicotinamide-Mononucleotide-Adenylyltransferase-for-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部The rational engineering of enzymes that coordinate multiple substrates within a confined active site remains a major challenge in biocatalysis. Here, we present a structure-guided dual-clus https://longbiosci.com/news/Structural-features-and-disease-associated-functions-ADGRV1-insights-from-signaling-2026.htmlhttps://longbiosci.com/news/Structural-features-and-disease-associated-functions-ADGRV1-insights-from-signaling-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Although the direct experimental evidence of ADGRV1 is currently limited, its predicted PBM suggests that similar PDZ-dependent regulatory mechanisms may appliable.In summary, ADGRV1 is a mu https://longbiosci.com/news/Structural-differentiation-and-collaborative-optimization-the-spatial-network-pension-2026.htmlhttps://longbiosci.com/news/Structural-differentiation-and-collaborative-optimization-the-spatial-network-pension-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Research on community-based integrated care (28) and long-term care utilization (29) further indicates that individual characteristics, family support, and institutional capacity jointly sha https://longbiosci.com/news/Stroke-and-cognitive-decline-associations-social-support-and-family-2026.htmlhttps://longbiosci.com/news/Stroke-and-cognitive-decline-associations-social-support-and-family-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Stroke is associated with accelerated cognitive decline in older adults, but whether social support and family connections statistically moderate this association has rarely been https://longbiosci.com/news/Stress-induced-Golgiphagy-sustains-tumor-promoting-glycosylation-breast-cancer-2026.htmlhttps://longbiosci.com/news/Stress-induced-Golgiphagy-sustains-tumor-promoting-glycosylation-breast-cancer-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Golgiphagy contributes to Golgi quality control, yet its regulatory mechanisms and physiological functions remain poorly understood. We identify the deubiquitinase USP28 as an upstream regul https://longbiosci.com/news/Stress-hyperglycemia-ratio-associated-with-delirium-elderly-cardiac-surgery-2026.htmlhttps://longbiosci.com/news/Stress-hyperglycemia-ratio-associated-with-delirium-elderly-cardiac-surgery-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部This postoperative period after cardiac surgery is marked by a biphasic metabolic crisis—transitioning from hypometabolism to sustained hypermetabolism—with features of insulin resistance, r https://longbiosci.com/news/Sti1-requires-its-Hsp70-interacting-regions-deposit-misfolded-proteins-the-2026.htmlhttps://longbiosci.com/news/Sti1-requires-its-Hsp70-interacting-regions-deposit-misfolded-proteins-the-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Protein homeostasis, or proteostasis, ensures a properly folded and functional proteome and is essential for cell survival. Proteins often misfold during stress or because of mutations that https://longbiosci.com/news/Stepwise-direct-reprogramming-adult-human-dermal-fibroblasts-into-tendon-like-2026.htmlhttps://longbiosci.com/news/Stepwise-direct-reprogramming-adult-human-dermal-fibroblasts-into-tendon-like-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部INTRODUCTION: Synthetic materials are widely used in pediatric surgery for congenital diaphragmatic hernia repair when primary closure is not feasible but remain associated with complication https://longbiosci.com/news/Stem-cell-therapies-for-chronic-obstructive-pulmonary-disease-mapping-2026.htmlhttps://longbiosci.com/news/Stem-cell-therapies-for-chronic-obstructive-pulmonary-disease-mapping-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部Overall, the publicly available studies reported no major short-term safety concerns for the specific cell products evaluated, whereas efficacy remained heterogeneous.；Our findings reveal a https://longbiosci.com/news/Statin-discontinuation-older-adults-does-frailty-matter-2026.htmlhttps://longbiosci.com/news/Statin-discontinuation-older-adults-does-frailty-matter-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部（PubMed 未提供摘要） https://longbiosci.com/news/Statewide-Trends-Morbidity-and-Mortality-Octogenarians-Undergoing-Isolated-Coronary-2026.htmlhttps://longbiosci.com/news/Statewide-Trends-Morbidity-and-Mortality-Octogenarians-Undergoing-Isolated-Coronary-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: We sought to determine whether advanced age modifies the association between established preoperative risk factors and 30-day outcomes following isolated coronary artery bypass g https://longbiosci.com/news/Spousal-Traumatic-Brain-Injury-and-Risk-Mortality-Dementia-and-2026.htmlhttps://longbiosci.com/news/Spousal-Traumatic-Brain-Injury-and-Risk-Mortality-Dementia-and-2026.htmlThu, 05 Nov 2026 00:00:00 +0000LongBiosci 编辑部IMPORTANCE: Traumatic brain injury (TBI) is highly prevalent in older adults. While there is strong and growing evidence that TBI is associated with caregiver burden and psychological health