https://longbiosci.com 最新生物医药与长寿科技研究资讯 zh-cn Tue, 03 Nov 2026 21:46:40 GMT https://longbiosci.com/news/White-matter-integrity-and-IL-6-mediation-type-diabetes-HABS-HD-2026.htmlhttps://longbiosci.com/news/White-matter-integrity-and-IL-6-mediation-type-diabetes-HABS-HD-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部T2DM 脑白质完整性与 IL-6 整合作用（HABS-HD 多族群） https://longbiosci.com/news/Vesalius-Longevity-Labs-RTO-Closing-FormD-30M-2026.htmlhttps://longbiosci.com/news/Vesalius-Longevity-Labs-RTO-Closing-FormD-30M-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部《行业情报周报_2026-11-04》投融资表 #1：原 Sweet Earth Holdings（CSE: SE，拟改代码 VLAB）于 2026-10-29 完成与 Vesalius Canada/SPV 的业务合并（statutory amalgamation），合并后总股本 100,828,947 股（fully diluted 117,063,697 股）；11-03 https://longbiosci.com/news/The-self-renewing-lymphoid-biased-hematopoietic-stem-cells-support-long-term-lymphopoiesis-2026.htmlhttps://longbiosci.com/news/The-self-renewing-lymphoid-biased-hematopoietic-stem-cells-support-long-term-lymphopoiesis-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部自我更新的淋巴偏向 HSC 支持小鼠终身淋巴造血 https://longbiosci.com/news/Tau-PET-Braak-staging-across-the-Alzheimer-Disease-continuum-2026.htmlhttps://longbiosci.com/news/Tau-PET-Braak-staging-across-the-Alzheimer-Disease-continuum-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部Tau PET Braak 分期跨 AD 疾病连续体：Flortaucipir vs MK6240 头对头 https://longbiosci.com/news/Target-Trial-Emulation-Metformin-for-Dementia-Prevention-All-Robustness-2026.htmlhttps://longbiosci.com/news/Target-Trial-Emulation-Metformin-for-Dementia-Prevention-All-Robustness-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部二甲双胍预防痴呆目标试验仿真（All of Us）：对队列与混杂定义的稳健性 https://longbiosci.com/news/SENgEAR-interactive-visualization-platform-for-comparative-analysis-senescence-signatures-2026.htmlhttps://longbiosci.com/news/SENgEAR-interactive-visualization-platform-for-comparative-analysis-senescence-signatures-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部SENgEAR：衰老签名与细胞通讯交互可视化平台 https://longbiosci.com/news/Recurrent-mitotic-error-and-purifying-selection-shape-chromosomal-mosaicism-2026.htmlhttps://longbiosci.com/news/Recurrent-mitotic-error-and-purifying-selection-shape-chromosomal-mosaicism-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部SMaHT 跨 19 组织染色体嵌合：反复有丝分裂错误 + 净化选择 https://longbiosci.com/news/Rare-variant-burden-analysis-E3-ubiquitin-ligase-genes-across-2026.htmlhttps://longbiosci.com/news/Rare-variant-burden-analysis-E3-ubiquitin-ligase-genes-across-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部E3 泛素连接酶基因多祖先稀有变异负荷分析：阴性结果 https://longbiosci.com/news/Quantitative-imaging-native-tissue-architecture-combined-with-deep-multi-omics-2026.htmlhttps://longbiosci.com/news/Quantitative-imaging-native-tissue-architecture-combined-with-deep-multi-omics-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部NORIGAMI：NoRI 定量成像 + 深度多组学解出肾脏衰老空间生物学 https://longbiosci.com/news/Prefrontal-cortex-transcriptomes-distinguish-Alzheimers-disease-from-asymptomatic-amyloid-2026.htmlhttps://longbiosci.com/news/Prefrontal-cortex-transcriptomes-distinguish-Alzheimers-disease-from-asymptomatic-amyloid-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部DLPFC 转录组区分症状性 AD 与 A+T− 病理性老化 https://longbiosci.com/news/Polygenic-risk-scores-and-plasma-biomarkers-young-onset-dementia-MiND-2026.htmlhttps://longbiosci.com/news/Polygenic-risk-scores-and-plasma-biomarkers-young-onset-dementia-MiND-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部早发型痴呆队列中 AD 与精神多基因风险互相独立、与血浆标志物无关 https://longbiosci.com/news/Polycomb-Marked-Promoter-Methylation-Gains-Aging-and-Cancer-are-2026.htmlhttps://longbiosci.com/news/Polycomb-Marked-Promoter-Methylation-Gains-Aging-and-Cancer-are-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部Polycomb 标记启动子甲基化获得独立于复制，追随“生物衰老” https://longbiosci.com/news/Organelle-Aging-Predicts-Human-Disease-2026.htmlhttps://longbiosci.com/news/Organelle-Aging-Predicts-Human-Disease-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部细胞器衰老预测人类疾病 https://longbiosci.com/news/Oligodendrocyte-precursor-cell-death-does-not-contribute-lifelong-population-2026.htmlhttps://longbiosci.com/news/Oligodendrocyte-precursor-cell-death-does-not-contribute-lifelong-population-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部OPC 死亡不参与终身群体稳态 https://longbiosci.com/news/Muna-MNA-001-Oral-TREM2-Agonist-Phase1-Positive-2026.htmlhttps://longbiosci.com/news/Muna-MNA-001-Oral-TREM2-Agonist-Phase1-Positive-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部《行业情报周报_2026-11-04》管线表 #3（🔄 新增基线条目）：Muna Therapeutics（Copenhagen & Boston）口服小分子 TREM2 激动剂 MNA-001——稳定可信号化 TREM2 于小胶质细胞表面，激活其清除碎片/调炎功能——随机双盲安慰剂对照 Ph1（SAD/MAD + 老年队列）阳性：无 SAE、无因不良反应脱落；CNS 暴露良好 https://longbiosci.com/news/Machine-learning-and-AI-approaches-for-detecting-caregiver-burden-2026.htmlhttps://longbiosci.com/news/Machine-learning-and-AI-approaches-for-detecting-caregiver-burden-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部会话转录检出痴呆照护负担：四种 ML/AI 对比 https://longbiosci.com/news/Integrated-metabolomics-and-proteomics-from-voxelated-cortical-hemispheres-adult-2026.htmlhttps://longbiosci.com/news/Integrated-metabolomics-and-proteomics-from-voxelated-cortical-hemispheres-adult-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部猕猴全皮层毫米级配对代谢组+蛋白组体素图谱 https://longbiosci.com/news/Inflammatory-proteostasis-reprogramming-creates-lysosomal-bottleneck-for-microglial-aggregate-2026.htmlhttps://longbiosci.com/news/Inflammatory-proteostasis-reprogramming-creates-lysosomal-bottleneck-for-microglial-aggregate-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部炎性蛋白稳态重编程造成小胶质细胞聚集体清除的溶酶体瓶颈 https://longbiosci.com/news/Immuno-Proteomic-Age-Cardiovascular-Etiology-iPACE-Signature-Predicts-Cardiovascular-Risk-2026.htmlhttps://longbiosci.com/news/Immuno-Proteomic-Age-Cardiovascular-Etiology-iPACE-Signature-Predicts-Cardiovascular-Risk-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部iPACE：30 蛋白免疫蛋白质组学年龄签名预测老年心血管风险 https://longbiosci.com/news/IMU-instrumented-daily-activities-quantify-PD-severity-and-functional-ability-2026.htmlhttps://longbiosci.com/news/IMU-instrumented-daily-activities-quantify-PD-severity-and-functional-ability-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部日常活动 IMU 短片段量化 PD 严重度与功能能力 https://longbiosci.com/news/Head-to-Head-Comparison-Flortaucipir-and-MK6240-tau-PET-Detect-Subtle-Objective-2026.htmlhttps://longbiosci.com/news/Head-to-Head-Comparison-Flortaucipir-and-MK6240-tau-PET-Detect-Subtle-Objective-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部tau-PET 头对头检出客观轻微认知损伤（SOCI） https://longbiosci.com/news/GDF15-modifies-NAD-salvage-pathway-and-dampens-immune-response-2026.htmlhttps://longbiosci.com/news/GDF15-modifies-NAD-salvage-pathway-and-dampens-immune-response-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部GDF15 调控 NAD+ 补救通路并抑制线粒体病免疫反应 https://longbiosci.com/news/Fertilization-offsets-the-maternal-age-effect-mouse-oocytes-provided-2026.htmlhttps://longbiosci.com/news/Fertilization-offsets-the-maternal-age-effect-mouse-oocytes-provided-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部受精抵消母源年龄对卵母细胞的影响——前提是输卵管不老 https://longbiosci.com/news/FDA-Potency-Assurance-Cell-Gene-Therapy-Guidance-2026.htmlhttps://longbiosci.com/news/FDA-Potency-Assurance-Cell-Gene-Therapy-Guidance-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部《行业情报周报_2026-11-04》监管表 #1：FDA 于 2026-11-03 发布《Potency Assurance for Cellular and Gene Therapy Products》行业指南（定稿，Availability，FR 2026-22427）——为细胞/基因治疗产品的效价（potency）保证给出框架，对 MSC/细胞疗法类长寿管线（Longe https://longbiosci.com/news/Exogenus-EXO-101-HorizonEurope-13M-Consortium-2026.htmlhttps://longbiosci.com/news/Exogenus-EXO-101-HorizonEurope-13M-Consortium-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部《行业情报周报_2026-11-04》管线表 #4（🔄 新增基线条目）：葡萄牙 Coimbra 的 Exogenus Therapeutics 牵头十方联盟（含 Lonza、Anthony Nolan、iLoF、Utrecht 大学/UMC、Maastricht UMC+ 等）获五年 €13M Horizon Europe 资助，推进 EXO-101——天然（非工程化）脐带血细 https://longbiosci.com/news/Enlivex-Allocetra-Knee-OA-12-Month-Topline-2026.htmlhttps://longbiosci.com/news/Enlivex-Allocetra-Knee-OA-12-Month-Topline-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部《行业情报周报_2026-11-04》管线表 #2（🔄 新增基线条目）：Enlivex（NASDAQ: ENLV）早期凋亡自体免疫细胞疗法 Allocetra-OTS（重置固有免疫、针对衰老相关免疫失调）中重度膝骨关节炎 Ph1/2a（ENX-CL-05-001，NCT06233474）12 个月随访顶线：64+ 人群临床有意义应答（疼痛减轻 + 膝功能改善）79.2% vs https://longbiosci.com/news/ECG-foundation-models-share-age-related-performance-disparity-that-originates-2026.htmlhttps://longbiosci.com/news/ECG-foundation-models-share-age-related-performance-disparity-that-originates-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部ECG 基础模型共有“年龄结构化”性能差距：源自数据而非模型 https://longbiosci.com/news/Diabetes-prevalence-and-determinants-among-adults-aged-India-LASI-2026.htmlhttps://longbiosci.com/news/Diabetes-prevalence-and-determinants-among-adults-aged-India-LASI-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部LASI 印度 45+ 糖尿病患病率与决定因素 https://longbiosci.com/news/Delayed-centrifugation-blood-collection-tube-for-remote-blood-biomarker-assessment-2026.htmlhttps://longbiosci.com/news/Delayed-centrifugation-blood-collection-tube-for-remote-blood-biomarker-assessment-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部延迟离心采血管对 p-tau217/Aβ42 稳定性的影响 https://longbiosci.com/news/Cumulus-cells-mediate-the-protective-effect-the-marine-carotenoid-2026.htmlhttps://longbiosci.com/news/Cumulus-cells-mediate-the-protective-effect-the-marine-carotenoid-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部岩藻黄素经卵丘细胞 NRF2 延缓排卵后卵母细胞衰老 https://longbiosci.com/news/Combined-continuous-STN-and-intermittent-NBM-DBS-for-cognition-2026.htmlhttps://longbiosci.com/news/Combined-continuous-STN-and-intermittent-NBM-DBS-for-cognition-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部NBM 间歇神经刺激带来临床意义认知改善（PD，n=5） https://longbiosci.com/news/Biophytis-BIO101-Brazil-Approval-OBA-Phase2-2026.htmlhttps://longbiosci.com/news/Biophytis-BIO101-Brazil-Approval-OBA-Phase2-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部《行业情报周报_2026-11-04》管线表 #1（⬆ 本期唯一阶段/资格推进）：Biophytis（Euronext Growth Paris: ALBPS）口服 MAS 受体（MAS1/2/3）激活剂 BIO101（Sarconeos，即 20-羟基蜕皮甾酮 20E）用于肌少症 + 肥胖，其 OBA 肥胖 Ph2 研究（疗效/安全性/PK，NCT07411378）获巴西监管 https://longbiosci.com/news/Autophagy-activator-AA-20-engages-CDK5-promote-lipophagy-and-improve-2026.htmlhttps://longbiosci.com/news/Autophagy-activator-AA-20-engages-CDK5-promote-lipophagy-and-improve-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部自噬激活剂 AA-20 咬合 CDK5 促脂噬、改善神经退行表型 https://longbiosci.com/news/Aging-reshapes-cardiac-extravascular-leukocyte-transcription-through-bidirectional-remodeling-2026.htmlhttps://longbiosci.com/news/Aging-reshapes-cardiac-extravascular-leukocyte-transcription-through-bidirectional-remodeling-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部衰老重塑心脏血管外白细胞转录（LPS 内毒素血症） https://longbiosci.com/news/Age-related-biological-dysregulation-quantified-using-metabolomics-composed-distinct-subsystems-2026.htmlhttps://longbiosci.com/news/Age-related-biological-dysregulation-quantified-using-metabolomics-composed-distinct-subsystems-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部CLSA 代谢组学生物失调由不同子系统构成，对健康结局协同 https://longbiosci.com/news/Age-based-shifts-multicellular-community-organization-and-abundance-HPV-Negative-Head-2026.htmlhttps://longbiosci.com/news/Age-based-shifts-multicellular-community-organization-and-abundance-HPV-Negative-Head-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部HPV 阴性头颈癌多细胞群落组织的年龄偏移 https://longbiosci.com/news/Age-Associated-Shifts-Toward-Anaerobic-Taxa-and-Amino-Acid-2026.htmlhttps://longbiosci.com/news/Age-Associated-Shifts-Toward-Anaerobic-Taxa-and-Amino-Acid-2026.htmlWed, 04 Nov 2026 00:00:00 +0000LongBiosci 编辑部犬口腔微生物组随龄向厌氧类群与氨基酸降解转移 https://longbiosci.com/news/microRNA-Loaded-Extracellular-Vesicles-Mechanisms-and-Therapeutic-Potential-Senescence-and-2026.htmlhttps://longbiosci.com/news/microRNA-Loaded-Extracellular-Vesicles-Mechanisms-and-Therapeutic-Potential-Senescence-and-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部Cellular senescence is a biological process characterized by stable cell cycle arrest that contributes to tumor suppression and tissue remodeling but can also promote aging-associated dysfun https://longbiosci.com/news/are-doing-the-best-can-realities-and-challenges-staff-2026.htmlhttps://longbiosci.com/news/are-doing-the-best-can-realities-and-challenges-staff-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部OBJECTIVES: This qualitative study explored the experiences and perspectives of in-home aged care staff supporting clients living with Complex Mental Health Issues (CMHI), including how thes https://longbiosci.com/news/Vortex-wave-stimulation-A-novel-anabolic-stimulus-for-ageing-2026.htmlhttps://longbiosci.com/news/Vortex-wave-stimulation-A-novel-anabolic-stimulus-for-ageing-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部（PubMed 未提供摘要） https://longbiosci.com/news/Understanding-the-experience-healthcare-providers-delivering-care-older-adults-2026.htmlhttps://longbiosci.com/news/Understanding-the-experience-healthcare-providers-delivering-care-older-adults-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Knowledge gaps remain regarding the current challenges of delivering care to meet the needs of older adults presenting in the Emergency department (ED). This study aimed to explo https://longbiosci.com/news/Ultrasound-Multifunctional-Physical-Platform-for-Whole-Grape-Valorization-From-Field-2026.htmlhttps://longbiosci.com/news/Ultrasound-Multifunctional-Physical-Platform-for-Whole-Grape-Valorization-From-Field-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部The grape and wine industry faces prolonged barrel aging, microbial spoilage, protein haze, chemical additives, and inefficient by-product valorization. These challenges motivate nonthermal https://longbiosci.com/news/Tributyl-phosphate-disrupts-neuronal-autophagy-potential-involvement-TLR4-cell-2026.htmlhttps://longbiosci.com/news/Tributyl-phosphate-disrupts-neuronal-autophagy-potential-involvement-TLR4-cell-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部Tributyl phosphate (TBP), a widely used organophosphate ester, exhibits lipophilic characteristics that enable it to cross the blood-brain barrier. Although its neurotoxicity has been confir https://longbiosci.com/news/Thioredoxin-System-Senescence-Ageing-Review-2026.htmlhttps://longbiosci.com/news/Thioredoxin-System-Senescence-Ageing-Review-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部Ageing Research Reviews 系统综述：Trx-1/Trx-2、TrxR1/R2 与 TXNIP 处在氧化应激、细胞衰老与年龄相关疾病的交汇点 https://longbiosci.com/news/The-hidden-work-vigilance-phenomenological-study-how-intensive-care-2026.htmlhttps://longbiosci.com/news/The-hidden-work-vigilance-phenomenological-study-how-intensive-care-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部PURPOSE: Older adults represent a growing proportion of intensive care unit (ICU) admissions, yet deterioration in this population is often subtle and atypical, requiring heightened nursing https://longbiosci.com/news/The-effects-regular-exercise-and-psychoeducation-quality-life-depression-2026.htmlhttps://longbiosci.com/news/The-effects-regular-exercise-and-psychoeducation-quality-life-depression-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Sarcopenia is a common geriatric syndrome associated with impaired physical function, depressive symptoms, and reduced quality of life. This trial aimed to compare the effects of https://longbiosci.com/news/The-double-edged-sword-digital-literacy-divergent-effects-subjective-and-objective-2026.htmlhttps://longbiosci.com/news/The-double-edged-sword-digital-literacy-divergent-effects-subjective-and-objective-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部AIM: To examine how subjective and objective digital literacy influences cognitive health among older adults. DESIGN: Longitudinal panel study using three waves of nationally representative https://longbiosci.com/news/The-Senescent-Macrophage-Central-Hub-Skeletal-Aging-Mechanisms-Niche-2026.htmlhttps://longbiosci.com/news/The-Senescent-Macrophage-Central-Hub-Skeletal-Aging-Mechanisms-Niche-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部Bone marrow macrophages (BMMs) coordinate skeletal remodelling, haematopoietic niche function, immune surveillance, and tissue repair. Whether a persistent senescent state in BMMs is a causa https://longbiosci.com/news/The-Need-for-Oral-Frailty-Prevention-and-Future-Tasks-2026.htmlhttps://longbiosci.com/news/The-Need-for-Oral-Frailty-Prevention-and-Future-Tasks-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部The Japanese Kashiwa cohort study followed 2,011 adults aged ≥65 years and found that participants with oral frailty, defined as impairment in at least three of six items and observed in 16% https://longbiosci.com/news/The-Invisible-Killer-Neurodegeneration-Mitochondrial-Dysfunction-Neurodegenerative-Disorders-Mechanisms-2026.htmlhttps://longbiosci.com/news/The-Invisible-Killer-Neurodegeneration-Mitochondrial-Dysfunction-Neurodegenerative-Disorders-Mechanisms-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部29 Collectively, these molecular defects lower oxidative‑phosphorylation efficiency, reduce cellular ATP supply and exacerbate electron leakage that fuels further ROS production.；Post‑mortem https://longbiosci.com/news/The-Hidden-Genome-Awakens-LINE-1-Retrotransposons-Emerging-Regulators-Cardiac-2026.htmlhttps://longbiosci.com/news/The-Hidden-Genome-Awakens-LINE-1-Retrotransposons-Emerging-Regulators-Cardiac-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部Cardiac aging is a major determinant of cardiovascular morbidity and mortality, characterized by progressive myocardial fibrosis, impaired contractile function, vascular dysfunction, and red https://longbiosci.com/news/The-Effects-Supplementing-Oil-and-Leucine-Nutrient-Transport-Sows-2026.htmlhttps://longbiosci.com/news/The-Effects-Supplementing-Oil-and-Leucine-Nutrient-Transport-Sows-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部This study investigated the effects of dietary soybean oil and leucine (Leu) supplementation during the peripartum and lactating periods on placental nutrient transport, offspring muscle dev https://longbiosci.com/news/The-Canadian-Morphea-Registry-Design-Baseline-Characteristics-and-Age-Related-2026.htmlhttps://longbiosci.com/news/The-Canadian-Morphea-Registry-Design-Baseline-Characteristics-and-Age-Related-2026.htmlTue, 03 Nov 2026 00:00:00 +0000LongBiosci 编辑部BACKGROUND: Morphea is a rare immune-mediated fibrosing skin disorder with heterogeneous clinical manifestations across the lifespan. Existing large cohorts have predominantly originated fro