同行评议人体研究

已在同行评议期刊发表的人体研究,包括随机对照试验、队列分析与临床试验中期数据。这是本站证据等级中可信度最高的一类。

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临床试验 A 2026-11-01 生命历程

Groups did not differ significantly at baseline on any assessed variable (all p > 0.05; Table , Table S2); however, non-significant tests do not estab…

研究进展 A 2026-11-01 器官衰老

The model’s residuals followed a normal distribution (p = 0.207) and exhibited constant variance across all levels of independent variables (p = 0.104…

研究进展 A 2026-11-01 神经退行

Specifically, PC1 effectively captures the convergence of cortical thickness and tissue density (i.e., how they vary together), while PC2 represents t…

研究进展 A 2026-11-01 代谢与营养

Moreover, advancing age is associated with increased corneal irregularity[46] , which could differentially affect diameter measurements depending on t…

研究进展 A 2026-11-01 器官衰老

In contrast, 40% heat‐inactivated NHS (HI‐NHS) had no significant hemolytic effect and was used as a negative control (Figure ).;Consistent with previ…

研究进展 A 2026-11-01 代谢与营养

No significant differences were observed between the two groups in age (67.15 ± 8.16 vs. 68.80 ± 8.77 years, P = 0.647), sex (4/9 vs. 5/5, P = 0.417),…

研究进展 A 2026-11-01 代谢与营养

Compared with infants without AKI, those who developed AKI were younger (median, 5.0 vs. 7.0 months; P = 0.001), had longer CPB duration (105 vs. 91 m…

研究进展 A 2026-11-01 器官衰老

Participants with cognitive frailty were older and more likely to be female, living in rural areas, and with lower educational levels compared with ro…

研究进展 A 2026-11-01 代谢与营养

Both RCF (HR=2.74, 95%CI:2.25-3.34) and PRCF (HR=2.51, 95%CI:1.96-3.21) were associated with increased CKM risk (both P<0.001).;RCF-to-Robust improvem…

研究进展 A 2026-11-01 器官衰老

Cochlear implants (CIs) provide essential auditory access for people who are deaf or hard-of-hearing. Over time, however, sound processors (SPs) becom…

研究进展 A 2026-11-01 生命历程

result from better clinical decisions, stronger therapeutic alliance, increased self-efficacy, more meaningful goals, changes in pain beliefs, greater…

流行病学 A 2026-11-01 器官衰老

Femoral neck BMD (FNBMD) was comparable across groups, but the lumbar spine BMD (LSBMD) was slightly higher in persons with two or more CHIP mutations…

研究进展 A 2026-11-01 生命历程

After selecting respondents aged 65 years or older, the analytical sample consisted of 13,020 participants.;Country-level analyses were restricted to …

研究进展 A 2026-11-01 生命历程

Secondary education and diploma-level education or higher accounted for 14.1% and 4.3%, respectively, while 5.7% had no education.;This partly explain…

研究进展 A 2026-11-01 细胞衰老

Among women, breast cancer mortality increased markedly after age 50, with approximately 80% of female deaths occurring in women aged 50 years and old…

流行病学 A 2026-11-01 神经退行

The proportion of childhood hunger in the case group was higher than that of the control group (76.62% vs. 69.48%, P < 0.001).;Meanwhile, the constitu…

研究进展 A 2026-11-01 免疫与炎症

Complete loss of Ctsb labeling was observed following treatment with 5 or 10 µM Z‐RK‐AOMK, indicating near‐complete inhibition of intracellular Ctsb a…

研究进展 A 2026-11-01 细胞衰老

The CSCC mortality rate among individuals aged 65 or older increases progressively with age, rising from 2.5 per 100, 000 population in those aged 65–…

研究进展 A 2026-11-01 细胞衰老

Kaplan–Meier survival analysis showed that patients with higher NQO1 expression exhibited a trend toward poorer overall survival compared with those w…

流行病学 A 2026-11-01 器官衰老

However, the proportion of women was higher in the stable low-risk cluster (cluster 1, n=1233, 76.9%) and lower in the high-risk cluster (cluster 4, n…

研究进展 A 2026-11-01 免疫与炎症

A 40‐year‐old female patient was diagnosed with stage IIE (breast) lymphoma associated with immune deficiency and dysregulation per WHO 2022 classific…

研究进展 A 2026-11-01 器官衰老

Application of Western cutoffs to the Thai populations results in significant overestimation of sarcopenia prevalence, emphasizing the critical import…

研究进展 A 2026-11-01 生命历程

The majority self-identified as men and homosexual, and most reported being either single or married/cohabiting.;Educational attainment within the sam…

研究进展 A 2026-11-01 神经退行

Across the study communities, there were significant differences in demographic characteristics.;Specifically, Chilenje participants were more likely …