时间标签：数据日期 2026-10-31 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/28–2026/10/31 ｜ 情报发生日期 2026-10-31
研究问题
However, as clinical management has improved, attention has increasingly shifted toward a broader understanding of health and quality of life in PLWH, extending beyond viral suppression alone (; ).；Despite effective viral suppression, many PLWH continue to experience a wide range of physical, psychological, and social challenges as they age, including comorbid conditions, like atherosclerosis, metabolic dysfunction, kidney disease, Parkinson’s disease, depression, and anxiety, the latter two often derived from stigma and/or socioeconomic disadvantage (; ; ; ; ; ; ; ).；To address this gap, our group previously developed and validated the Clinic Screening Tool for HIV (CST-HIV), a short PROM specifically designed to systematically identify eight core areas of concern for PLWH: anticipated stigma, emotional distress, sexuality, social support, material deprivation, sleep and fatigue, cognit
方法
We designed a cross-sectional study within the Spanish CoRIS cohort.；CoRIS is an open, multicentre prospective cohort of HIV-positive adults, who were naïve to antiretroviral treatment at study entry, recruited since January 2004 from any of the 48 centers across 14 of the 17 autonomous regions in the Spanish public healthcare system ().；The general inclusion criteria were having an HIV-positive diagnosis, being at least 18 years old, and not having any severe psychiatric or cognitive disorders.；The procedures for collecting self-reported measures involved providing participants with access to a unique link to download a dedicated mobile application, which enabled them to complete the online questionnaire.
核心结论
The majority self-identified as men and homosexual, and most reported being either single or married/cohabiting.；Educational attainment within the sample was generally high, with most having completed secondary or higher education.；In terms of employment, the majority were active in the workforce, while smaller groups were retired, unemployed, or students (). ‖ 结论：From a person-centered care perspective, these findings support the use of CST-HIV to identify both common and subgroup-specific priorities that might otherwise be overlooked in time-pressured consultations (; ).
局限
Cross-sectionally, higher material deprivation and anticipated stigma were associated with lower CD4+ cell counts.；Although collinearity diagnostics indicated no problematic multicollinearity among CST-HIV domains (VIFs = 1.12–2.05; tolerances = 0.49–0.90), these diagnostics do not explain the direction of the association or exclude residual confounding.；Selection processes related to survival, continued attendance in care, and availability of complete data also cannot be excluded.
对本项目的价值
★☆☆☆☆ 干预证据决定参照标准效应量——任何抗衰干预的收益至少应对标该基线。设计 cross-sectional。
全文来源
PMC JATS 全文（正文 31,956 字符，已过标题/DOI 逐字归属校验）
原文题录
- 英文标题：Validity evidence for the Clinic Screening Tool for HIV (CST-HIV) addressing factors that undermine health-related quality of life in people living with HIV.
- 期刊与标识：Front Psychol · PMID 42964230 · DOI 10.3389/fpsyg.2026.1940441
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
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