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基础研究 B 2026-11-01 代谢与营养

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基础研究 B 2026-11-01 代谢与营养

These findings establish that UBE3A is expressed in neuronal populations involved in the regulation of feeding behavior and systemic metabolism.;Hypot…

基础研究 B 2026-11-01 细胞衰老

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基础研究 B 2026-11-01 神经退行

Transmission electron microscopy (TEM) images revealed that the isolated EXO exhibited a predominantly spherical or near-spherical vesicular morpholog…

基础研究 B 2026-11-01 细胞衰老

The bands associated with the asymmetric and symmetric stretching vibrations of the carboxylate (COO−) groups are observed between 1,621 cm-1 and 1,42…

基础研究 B 2026-11-01 神经退行

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基础研究 B 2026-11-01 方法与工具

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基础研究 B 2026-11-01 生命历程

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综述解读 C 2026-11-01 器官衰老

Current diagnostic thresholds are essential clinical anchors, but they are not primarily designed to detect the earliest biological alterations associ…

流行病学 A 2026-11-01 器官衰老

The inter‑rater agreement for the CBCT‑based diagnosis of TMJOA between the two specialists was excellent, with a Cohen’s kappa of 0.81 (95% CI: 0.741…

基础研究 B 2026-11-01 器官衰老

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方法学 C 2026-11-01 方法与工具

In this context, metabolomics investigates metabolic changes associated with genetic predisposition, environmental exposures, nutrition, lifestyle, an…

产业动态 B 2026-11-01 产业

NCT06274749 于 2026-10-30 更新为干预性、招募中,计划 180 例、人群扩到 ≥55 岁健康成人;尿石素 A 作为线粒体自噬激活剂已有老年人肌肉耐力数据,本试验是其向临床终点证据过渡的一步。

基础研究 B 2026-11-01 代谢与营养

Mitophagy-associated markers and mitochondrial function were assessed by Western blotting, quantitative real-time PCR, mitochondrial DNA (mtDNA) integ…

基础研究 B 2026-11-01 代谢与营养

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综述解读 C 2026-11-01 神经退行

Varicella zoster virus (VZV) reactivation has emerged as a potential contributor to dementia through vascular and inflammatory mechanisms, with herpes…

研究进展 A 2026-11-01 神经退行

However, global epidemiological registries reveal a profound shift: while childhood varicella-preventative immunization programs have reduced pediatri…

基础研究 B 2026-11-01 神经退行

The neurological examination revealed a mild rigidity, postural instability, diffuse muscle weakness in upper and lower limbs, accentuated tendon refl…

研究进展 A 2026-11-01 免疫与炎症

Previous reports on RTEL1 ‐associated enterocolitis have documented its refractoriness to standard IBD treatments. , Patients with HHS exhibit combine…

流行病学 A 2026-11-01 生命历程

Gender distribution differed significantly by diet group, with a higher proportion of males among vegetarians (n = 147; 61.3%) compared to non-vegetar…

基础研究 B 2026-11-01 器官衰老

Vertebral fractures represent one of the most common manifestations of skeletal fragility and contribute substantially to morbidity, disability, and h…

研究进展 A 2026-11-01 生命历程

Post-intervention, VR participants showed markedly lower agitation scores (NPI) (4.2 ± 1.9 vs. 1.7 ± 1.2, p < 0.001), MMSE scores (23.5 ± 2.1 vs. 27.1…

流行病学 A 2026-11-01 代谢与营养

The prevalence of vitamin B12 deficiency differed significantly according to sex, duration of diabetes, and alcohol consumption (p < 0.05).;Specifical…

观点评论 C 2026-11-01 代谢与营养

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研究进展 A 2026-11-01 代谢与营养

The permutation test used the 1,000 label permutations stated in the Methods; none of the 1,000 permuted datasets reached the observed R2Y or Q2 (perm…

基础研究 B 2026-11-01 器官衰老

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基础研究 B 2026-11-01 生命历程

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基础研究 B 2026-11-01 生命历程

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基础研究 B 2026-11-01 生命历程

Higher total serum IgG levels have been associated with protection from cardiovascular events in ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial). An…

综述解读 C 2026-11-01 器官衰老

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