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Metabolically stressed hepatocytes may undergo reversible adaptation, cell death, or other stress responses; senescence should therefore be viewed as …

Over a lifetime, higher organisms sustain continuous biochemical, molecular, and cellular damage.；Once expanded ex vivo, human MSCs are defined by pla…

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Similarly, low ANGPT1 was significantly associated with an increased risk of low ASM and sarcopenia in the univariate analysis, Model 1, and Model 2 (…

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Combining serum NDEV mtDNA with Aβ40, p-Tau 217, GFAP, or APOE ε4 individually significantly improved diagnostic accuracy compared with single-indicat…

No items were eliminated or added, and the five-point Likert-type response scale was maintained.；Because the original expert-review process did not re…

GeroScience 研究：芝麻木酚素 sesaminol 可减轻酒精诱导的中年小鼠结肠细胞衰老，机理上可能涉及 AhR–Nrf2 轴。

Compared with women, men were more likely to be better educated and hold an undergraduate/postgraduate degree (p < 0.0001).；Men also reported higher a…

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Of the 6,157 individuals followed up in the 9th wave, 1,752 were excluded for not undergoing the K-MMSE, 37 were excluded due to dementia (36 previous…

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The effects of flexible dentures and reline materials, as well as their interaction, significantly influenced SBS (P < .001).；The Bright-U and TFDH-U …

Participants completed the SFS, the performance-based Modified Fried Frailty Scale (MFS), and the FRAIL scale.；We assessed internal consistency, const…

However, how intranasal mesenchymal stem cell administration is associated with these cell type-specific responses remains incompletely understood.；In…

To characterize cellular alterations associated with OA progression and joint aging, we performed single‐cell RNA sequencing on knee‐joint tissues col…

In both sexes, patients were evenly distributed by age group, with five individuals younger than 18 years and five aged 18 years or older.；As expected…

Among the five iMCD-TAFRO patients with active disease, 4 of 5 (80%; 95% CI 28–99; Cases 4, 6, 7, and 8) met the prespecified response criterion at 3 …

ANOVA results indicated no significant effects of sequence, period, or formulation on the ln-transformed pharmacokinetic parameters of sitagliptin und…

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Memory retention for non-interference pairs was lower than memory performance for interference pairs, but these differences were not statistically sig…

Regarding the average time from emergency trigger to successful pre-entry activation, when the smart emergency button is pressed and held for 3 second…

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Upon assessment, 41 studies were deemed to overall have low risk of bias, and 1 study was considered to have moderate risk; see Supplementary Material…

After applying the exclusion criteria described above (lack of available ADI data and age under 50), the final analytic sample comprised 3,172 partici…