数据日期 2026-10-29 · 生成时间 2026-10-29 06:03
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
Speech-in-noise (SIN) perception is a difficult everyday listening task that becomes more difficult with age.
方法
Participants (N = 83) monitored a continuous stream of syllables (~4.5 Hz) presented in quiet and noise conditions during EEG recordings.；We assessed neural phase-locking value (PLV) to the acoustic speech envelope to investigate interactions between aging, hearing loss, and stimulus noise on neural synchronization to speech.
核心结论
How aging impacts neural tracking of speech and behavioral decrements in SIN perception remains unclear.；To address these questions, we measured neural speech tracking during a continuous SIN perception task in younger and older adults via multichannel electroencephalography (EEG).；We assessed neural phase-locking value (PLV) to the acoustic speech envelope to investigate interactions between aging, hearing loss, and stimulus noise on neural synchronization to speech. ‖ 结论：Our results support the decline-compensation hypothesis, corroborate unusually large speech envelope encoding in older listeners, and suggest more robust neural synchronization to the speech signal is not always perceptually advantageous.
局限
未能获取全文，具体设计细节、失访与统计学处理无法核验。
对本项目的价值
★★★☆☆ 皮肤是唯一可直接局部给药、可活检、可影像量化的器官，最快可验证 senotherapeutic 概念。
原文题录
- 英文标题：Age- and noise-related differences in neural entrainment to speech sounds.
- 期刊与标识：Neurobiol Aging · PMID 42945789 · DOI 10.1016/j.neurobiolaging.2026.10.005**
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。