数据日期 2026-10-29 · 生成时间 2026-10-29 06:03
研究问题
This study investigated the effects of microencapsulated sodium butyrate (MSB) on production performance, reproductive hormone profiles, and gut microbiota-metabolite interactions in late-laying quails.
方法
Animals and diet A total of 400 healthy Korean laying quails (8 months old, a laying-type strain derived from Japanese quail) with similar laying performance were randomly divided into two groups with four replicates per group (50 birds/ replicate).；The dosage of 500 mg/kg was selected based on the manufacturer’s rec- ommendation for poultry use.；Animal Microbiome (2026) 8:108 Laying performance Throughout the trial, eggs from each group were col- lected and weighed once daily.
核心结论
Over the entire experimental period, the overall laying rate in the MSB group (76.25±2.6%) was signifi- cantly higher than that in the CON group (65.50±6.89%).；During weeks 1–4, the laying rate was 77.68±2.71% in the MSB group com- pared to 64.62±8.76% in the CON group (P<0.05).；It remained elevated in the MSB group at 74.82±3.15%, relative to 66.37±5.15% in CON group during weeks 5–8 (P<0.05). ‖ 结论：These benefits are likely driven by MSB-induced shifts in gut microbiota and metabolite profiles that support reproductive endocrine function, highlighting MSB as a practical microbiota-targeted strategy to help extend the productive lifespan of laying poultry.
局限
Beyond identifying MSB-responsive bacterial taxa and metabolites, our mediation analysis provided preliminary mechanistic clues linking microbial shifts to host repro- ductive physiology.；However, several important limitations warrant consid- eration.
对本项目的价值
★★★★☆ 方法学进展决定我们能否在有限样本下检出真实效应，属基础设施级收益。命中核心 微生物组；最大样本量约 4；设计 多组学。
全文来源
BMC OA PDF（正文 55,728 字符，已过标题/DOI 逐字归属校验）
原文题录
- 英文标题：Multi-omics insights into the role of microencapsulated sodium butyrate on production performance in aged quails.
- 期刊与标识：Anim Microbiome · PMID 42947196 · DOI 10.1186/s42523-026-00590-5**
B 级证据分级：B 级（同行评议临床前研究，主要为动物模型）
本文核心结论来自动物模型或体外细胞学，属临床前证据，不能外推至人体。「延长健康寿命」「改善功能」等表述在小鼠中的意义，与人类临床结局之间仍有距离。
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