数据日期 2026-10-29 · 生成时间 2026-10-29 06:03
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
Oral frailty, characterized by tooth loss, chewing difficulty, and swallowing problems, has been associated with adverse health outcomes in older adults.
方法
This cohort study aimed to examine community-level inequalities in the incidence of oral frailty and identify individual- and municipality-level factors associated with its onset among older adults in Japan.；We analyzed data from 42,987 participants aged ≥65 y who completed the Japan Gerontological Evaluation Study surveys in 2019 and 2022.；Modified multilevel Poisson regression was used to estimate incidence rate ratios.
核心结论
We analyzed data from 42,987 participants aged ≥65 y who completed the Japan Gerontological Evaluation Study surveys in 2019 and 2022.；Oral frailty was determined using a validated prediction model including age, number of teeth, chewing difficulty, and choking.；Individual-level variables included sociodemographic, health status, and social capital indicators. ‖ 结论：These findings highlight the importance of integrating individual risk-based prevention with community strategies that may contribute to reducing oral frailty and related oral health disparities in aging populations.
局限
未能获取全文，具体设计细节、失访与统计学处理无法核验。
对本项目的价值
★★☆☆☆ 衰弱/肌少症是少有的已有监管认可终点的老年综合征，是临床转化的最短路径。
原文题录
- 英文标题：Community-Level Inequalities and Risk Factors for Incident Oral Frailty.
- 期刊与标识：JDR Clin Trans Res · PMID 42937247 · DOI 10.1177/23800844261491726**
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。