时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
Circadian rhythms are endogenous, approximately 24-hour oscillations that align physiology and behavior with the environmental light-dark cycle and support homeostasis. In mammals, the suprachiasmatic nucleus (SCN) serves as the central circadian pacemaker, but its neuronal projections are restricted to a relatively small set of hypothala…
对本项目的价值
参考价值：属「脑老化与神经退行」方向；脑老化 / 神经退行 / 认知栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.5/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名：下丘脑室旁核作为昼夜节律调控的整合枢纽与疾病治疗靶点
- 英文标题：The Hypothalamic Paraventricular Nucleus as an Integrative Hub of Circadian Regulation and a Therapeutic Target in Disease.
- 期刊与标识：Pharmacological research · PMID 42971417 · DOI 10.1016/j.phrs.2026.109728