流行病学

基于年龄、NRS-2002 与 ADL 的老年髋部骨折术后谵妄床旁简化预测模型:回顾性队列研究

来源:Frontiers in psychiatry · PMID 42974212 · DOI 10.3389/fpsyt.2026.1963389 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-05 期 · 全文级(file_id dAlZBwueyWSz,实际下载核验 1,395,640 B) · 全文已获取并通过三重归属校验

时间标签:数据日期 2026-11-05 · 生成时间 2026-11-05 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 | 情报发生日期 2026-11-05

研究问题

The model should accordingly be read as a preliminary bedside screening model, not a comprehensive etiological risk model; multi-variable prospective cohorts are needed to test whether the omitted domains add performance.Several limitations merit emphasis.

方法

Despite its clinical importance, POD prediction in elderly hip fracture patients remains inadequate.;In this study, we sought to develop a simplified rule-out screening model using only information immediately available at the bedside upon emergency admission.;We prioritized high negative predictive value to safely identify low-risk patients who may not require intensive delirium prevention measures.Materials and methodsStudy design and populationThis single-center retrospective cohort study included patients aged >=60 years who underwent hip fracture surgery at Chengdu Fifth People’s Hospital between January 2019 and August 2023.

核心结论

The Nagelkerke R-squared of 0.241 indicates that these three variables explain a modest proportion of POD variance, consistent with the multifactorial nature of delirium.

局限

This estimate, however, warrants explicit caution.;The model should accordingly be read as a preliminary bedside screening model, not a comprehensive etiological risk model; multi-variable prospective cohorts are needed to test whether the omitted domains add performance.Several limitations merit emphasis.;This approach risks missing hypoactive delirium episodes, which would bias estimates toward the null, so the reported associations are likely conservative; differential misclassification cannot, however, be excluded, and conclusions are worded accordingly.

对本项目的价值

中等价值:属「脑老化与神经退行」方向;脑老化 / 神经退行 / 认知栏目可用作本项目文献库与综述素材。 | 价值分 2.6/5(★★★☆☆)

全文来源

PubMed PMC JATS(正文 25,341 字符,题名指纹 0.95,已过 PubMed PMCID 官方关联 + 题名指纹 + 正文长度归属校验)

原文题录

  • 中文题名:基于年龄、NRS-2002 与 ADL 的老年髋部骨折术后谵妄床旁简化预测模型:回顾性队列研究
  • 英文标题:A simplified bedside model using age, NRS-2002, and ADL to predict postoperative delirium in elderly hip fracture patients: a retrospective cohort study.
  • 期刊与标识:Frontiers in psychiatry · PMID 42974212 · DOI 10.3389/fpsyt.2026.1963389 · PMC PMC13725447

A 级证据分级:A 级(同行评议人体研究)

本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。

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