时间标签：数据日期 2026-10-31 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/28–2026/10/31 ｜ 情报发生日期 2026-10-31
研究问题
Diabetic retinopathy (DR) remains a leading cause of preventable vision loss among adults, affecting approximately 9.6 million individuals with diabetes in the United States, of whom 1.84 million have vision-threatening disease (VTD) [,].；Despite the effectiveness of early detection and treatment, a substantial care gap persists: only 66% of adults with diabetes undergo annual eye examination [], and up to 73% of individuals over 40 years of age with DR remain unaware of their diagnosis [].；Point-of-care diabetic retinopathy examination programs (POCDREP) have expanded access to screening; however, follow-up after screening remains inconsistent, with reported rates ranging from 30% to 75% [–].
方法
This retrospective cohort study evaluated six-month follow-up among adults (≥18 years) undergoing DREs at 75 primary care clinics within the POCDREP network between 2017 and 2019, with analyses restricted to examinations that resulted in a recommendation for follow-up with an ophthalmologist or optometrist.；Electronic medical records (EMRs) were used to extract patient-, clinical-, and system-level variables, including the primary outcome of loss to follow-up.；Among the 35 equipped clinics, 77.1% (n = 27) were part of the UPMC primary care network, 20% (n = 7) were University of Pittsburgh Physician Offices, and one was a free clinic (2.9%).；Based on imaging interpretation, follow-up was recommended in the presence of clinically significant findings, including moderate or worse DR or DR with macular exudates [,], other ocular pathologies such as age-related macular degeneration (AMD), su
核心结论
The median number of emergency room visits within six months before or after the DRE was 0 (IQR: 0–1).；Marital status was significantly associated with follow-up, with higher completion among married individuals compared to those not married (35.3% vs. 29.9%; p = 0.004) as shown in .；No other sociodemographic or economic variables were significantly associated with follow-up status (all p > 0.05). ‖ 结论：Overall, these findings suggest that the associations observed in the main models were generally consistent across the subgroups examined.
局限
Geographic variables were not included due to identifiability concerns, and the proportion of Latino patients in our cohort was low (2.5%) [], limiting statistical power to evaluate ethnic differences.；Nonetheless, qualitative research indicate that poverty and lack of insurance remain barriers to ongoing ophthalmic care [,].；Differences in population characteristics, socioeconomic measures, and study design may therefore explain the lack of association observed in our analysis.
对本项目的价值
★☆☆☆☆ 代谢轴既干预敏感性最高，也是老药新用供给最充足的来源。最大样本量约 3,121。
全文来源
PMC JATS 全文（正文 39,503 字符，已过标题/DOI 逐字归属校验）
原文题录
- 英文标题：Factors associated with loss to follow-up after point-of-care diabetic retinopathy examination in a teleophthalmology program: A retrospective cohort study.
- 期刊与标识：PLoS One · PMID 42955996 · DOI 10.1371/journal.pone.0359305
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
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