时间标签：数据日期 2026-10-31 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/28–2026/10/31 ｜ 情报发生日期 2026-10-31
研究问题
A strong and durable bond ensures mechanical integrity at the framework-veneer interface, hinders interfacial gap formation, and prevents the above-mentioned failure modes under intraoral conditions, where cyclic occlusal forces and thermal fluctuations are constantly at play.
方法
A total of 208 rectangular zirconia frameworks were fabricated by LCM and CNC techniques (n = 104 per technique).；The specimens for each above-mentioned fabrication group were randomly allocated into 4 groups in accordance with the surface conditioning strategy implemented on the veneering surface: C, APA, TSC, and GRD (n = 26 per strategy). • The veneering surfaces of the C group specimens were left untreated.• The veneering surfaces of the APA group specimens were abraded (Basic master; Renfert) with 110-µm Al2O3 particles (Cobra Aluoxyd; Renfert) at 0.2 MPa pressure perpendicularly from a 10-mm distance for 15 seconds.；In each surface conditioning strategy, the specimens were further divided into two subgroups as non-aged (TA[-]) and thermally-aged (TA[+]) (n = 13 per group).
核心结论
The overall model was statistically significant and explained a very large proportion of the variance in SBS (R2 = 0.964, adjusted R2 = 0.961).；The 3-way interaction among fabrication technique, surface-conditioning strategy, and thermal aging was not statistically significant, F(3,192) = 1.467, P = .225, ηp2 = 0.022, indicating that the combined effects of fabrication technique and surface conditioning on SBS were consistent across aging conditions.；Significant 2-way interactions were observed between fabrication technique and surface-conditioning strategy, F(3,192) = 5.166, P = .002, ηp2 = 0.075, and between surface-conditioning strategy and thermal aging, F(3,192) = 4.331, P = .006, ηp2 = 0.063. ‖ 结论：Within the limitations of this in vitro study, the following conclusions were drawn: 1.
局限
However, when TSC is not available, APA may serve as the nearest practical alternative in clinical settings, although it may not achieve the same SBS.；The predominance of adhesive failures can be attributed to the inherent limitations of SBS testing, which concentrates stresses at the zirconia-ceramic interface and promotes crack initiation at this region.；Although both groups were sintered at similar final temperature and dwell time, differences in the overall thermal processing protocols should be acknowledged as a limitation.
对本项目的价值
★☆☆☆☆ 相关范围内，作为背景与横向对照收录。
全文来源
PMC JATS 全文（正文 29,756 字符，已过标题/DOI 逐字归属校验）
原文题录
- 英文标题：Influence of surface-conditioning strategies on the shear bond strength of veneering ceramic to aged and non-aged zirconia frameworks fabricated with milling and 3D-printing.
- 期刊与标识：J Adv Prosthodont · PMID 42948551 · DOI 10.4047/jap.2026.18.5.420
B 级证据分级：B 级（同行评议临床前研究，主要为动物模型）
本文核心结论来自动物模型或体外细胞学，属临床前证据，不能外推至人体。「延长健康寿命」「改善功能」等表述在小鼠中的意义，与人类临床结局之间仍有距离。
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