时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
研究问题
Specifically, we hypothesized greater cognitive improvements in the music group (COGTEL‐WS and subtests) and greater sensorimotor improvements in the psychomotor group, particularly in laterality measures assessing body‐schema awareness.；Comparisons within this parsimonious set were adjusted for multiple testing using the Holm procedure.Partial correlations (controlling for Age and Site) examined whether homework duration was associated with training benefits: categorical fluency and verbal short‐term memory in MUS, and foot laterality in PM.；In contrast, the PM group showed a relative advantage in Foot Laterality Recognition Accuracy, although neither group exhibited significant within‐group changes (MUS mean = –0.38, SE = 0.27, p Holm = 0.17; PM mean = 0.47, SE = 0.31, p Holm = 0.12).Additionally, we examined whether training intensity influenced the above‐reported between‐group differences for Categorical Fluency, Verbal Short‐Term Memory, and Foot Laterality recognition.
方法
Specifically in Alzheimer's disease (AD) and MCI patients, musical activities have been shown to benefit general cognition, executive function, episodic memory, verbal fluency, emotional well‐being, and mood [21−25].Previous intervention studies provide an important context for the present design.；Group‐based psychomotor interventions in community‐dwelling older adults improved processing speed, executive functions, attention, reaction time, and mobility, with particularly pronounced benefits in lower‐functioning participants [34].；Across community‐dwelling older adults and patients with MCI or AD, psychomotor approaches have been shown to benefit cognition, well‐being, and quality of life, as well as sensorimotor abilities including balance, gait, and mobility [34−40].Music practice and psychomotor interventions are both ecologically meaningful and well‐suited for older adults, particularly when offered in group settings that promote sustained engagement and social connection in the post‐retirement period [41, 42].From a neurobiological standpoint, MCI is characterized by vulnerability in specific brain systems.
核心结论
From a cognitive perspective, speech‐in‐noise perception relies on higher‐order auditory cognitive processes, including selective attention, inhibition, working memory, and auditory–motor integration [10].Recent global epidemiological evidence indicates that the overall prevalence of MCI in the geriatric population is high (∼23.7%).；Together, these findings highlight the hippocampus as relevant for assessing potential intervention‐related changes in MCI.；Overall, MCI participants showed greater multidomain improvement than HC (HC‐MCI estimated marginal mean comparison = −0.35, SE = 0.17, p = 0.04).FIGURE 3Estimated marginal mean changes over 6 months (T2−T0 z‐scores) for each psychometric measure in HC and MCI participants.
局限
However, distinct cutoffs are often applied in clinical settings to improve specificity and to distinguish MCI from more advanced neurocognitive impairment.；However, all testing followed structured protocols to minimize bias.All participants included in the analyses were able to complete the full assessment battery.；However, the three measures included in the parsimonious model were not individually prespecified and were partly selected based on the observed data.
对本项目的价值
中高价值：属「脑老化与神经退行」方向；脑老化 / 神经退行 / 认知栏目可用作本项目文献库与综述素材。 ｜ 价值分 3.2/5（★★★☆☆）
全文来源
PubMed PMC JATS（正文 68,996 字符，题名指纹 0.93，已过 PubMed PMCID 官方关联 + 题名指纹 + 正文长度归属校验）
原文题录
- 中文题名：轻度认知障碍半年音乐训练与心理运动干预的比较：行为与海马结局
- 英文标题：Six-Month Music Practice Versus Psychomotor Interventions in Mild Cognitive Impairment: Behavioral and Hippocampal Outcomes.
- 期刊与标识：Annals of the New York Academy of Sciences · PMID 42969860 · DOI 10.1111/nyas.70433 · PMC PMC13726704