时间标签:数据日期 2026-11-03 · 生成时间 2026-11-03 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 | 情报发生日期 2026-11-03
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摘要(PubMed 原文节选)
BACKGROUND: Acute decompensated heart failure (ADHF) is the most common cause of hospitalization in older adults. Cellular senescence, a hallmark of aging biology, has been implicated in heart failure pathophysiology and functional decline via the pro-inflammatory senescence-associated secretory phenotype (SASP). We evaluated the association between SASP and physical function in older adults hospitalized for ADHF. METHODS: REHAB-HF was a trial of older adults hospitalized for ADHF randomized to a novel physical rehabilitation intervention or attention control. We measured a panel of 18-SASP analytes at in-hospital baseline and at 3-month follow-up. Outcomes included short physical performanc…
对本项目的价值
中高价值:属「衰老细胞清除 / SASP 轴」方向;细胞衰老 / senolytics / SASP栏目可用作本项目文献库与综述素材。 | 价值分 3.5/5(★★★★☆)
全文不可及原因
无 PMCID 且 OpenAlex / Unpaywall 未提供可下载 OA PDF
原文题录
- 中文题名:衰老生物标志物预测心衰住院后躯体功能与临床结局:REHAB-HF 的启示
- 英文标题:Senescence Biomarkers Predict Physical Function and Clinical Outcomes After Heart Failure Hospitalization: Insights From REHAB-HF.
- 期刊与标识:J Gerontol A Biol Sci Med Sci · PMID 42968386 · DOI 10.1093/gerona/glag256 · EDAT 2026-11-02