时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
研究问题
The sample size calculation was based on the primary objective of estimating PRISm prevalence and was not specifically powered for the secondary multinomial logistic regression analyses.Data CollectionData collection was conducted using I Field, a web-based data collection system.；Furthermore, since these do not fall into our study objectives, and since our data was not geared towards identifying asthma, we elected to classify these PFTs as “others” and not analyze them further.Measurement ToolThe questionnaire collected data on sociodemographic characteristics (eg, age, sex, height, weight), lifestyle factors (eg, fruit and vegetable consumption), and detailed smoking history (status, type, duration, and exposure to secondhand smoke).；Nevertheless, spirometry-based assessment ensured objective identification of airflow limitation among participants.
方法
Accordingly, this study aimed to estimate PRISm prevalence among Lebanese adults aged 40 years or above living in Beirut and Mount Lebanon governorates using spirometry testing, identify associated factors, and assess its relationship with QoL, while adjusting for relevant confounders.MethodsStudy Design, Participants, and Inclusion and Exclusion CriteriaA cross-sectional study was carried out between August and November 2025, using a multistage cluster sampling.；Participants with lung cancer, lung fibrosis, or lung resection surgery were excluded.；The study was approved by the Lebanese American University institutional review board (IRB number: LAU.SOM.ZA3.16/May/2024).Sample Size CalculationUsing Epi info 7.2.6.0, and assuming a PRISm prevalence ranging from 6 to 17.6%,5–7 with a 95% confidence level, a 4% margin of error, and a 5% anticipated non-response rate, the minimum sample was estimated at 740 participants, after adjusting for the multistage cluster sampling.
核心结论
These findings not only advance regional knowledge on PRISm but also offer actionable insights for prevention strategies, health system planning, and resource allocation in similar national settings.；These findings highlight the importance of targeted symptom management and closer clinical monitoring mainly of individuals with established respiratory disease, women, and those experiencing chronic respiratory symptoms.However, given the heterogeneous nature of PRISm, further longitudinal studies are needed to better define its natural history and guide evidence-based prevention and management strategies.
局限
Despite the strengths, several limitations should be acknowledged.；However, the random selection of participants within Beirut and Mount Lebanon minimized selection bias and enhanced the representativeness of the sample within these governorates.；However, as the first study of PRISm in the region, it provides a robust foundation for future research and public health initiatives.
对本项目的价值
中等价值：属「衰老机制与老年临床」方向；其他衰老相关栏目可用作本项目文献库与综述素材。 ｜ 价值分 2.6/5（★★★☆☆）
全文来源
PubMed PMC JATS（正文 43,622 字符，题名指纹 0.88，已过 PubMed PMCID 官方关联 + 题名指纹 + 正文长度归属校验）
原文题录
- 中文题名：低中收入国家 PRISm（肺量计测定受限但未达 COPD）患病率、相关因素与生活质量：横断面研究
- 英文标题：Prevalence, Associated Factors and Quality of Life in PRISm: Findings from a Cross-Sectional Study in a Low- to Middle-Income Country.
- 期刊与标识：International journal of chronic obstructive pulmonary disease · PMID 42979153 · DOI 10.2147/COPD.S627414 · PMC PMC13729856