数据日期 2026-10-29 · 生成时间 2026-10-29 06:03
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
Alzheimer's disease (AD) is a serious kind of pathology that mainly affects older adults and significantly reduces the quality of their life.
方法
Despite decades of research, the pathogenesis of AD, the causes and the trigger mechanism of its occurrence remain the subject of debate.
核心结论
This review examines hypotheses of the pathogenesis of AD, including the involvement of amyloid-β peptide and hyperphosphorylated tau protein fragments in neuroinflammation and neurodegeneration.；It also discusses potential therapies for AD based on peptides that target various aspects of the disease's pathogenesis. ‖ 结论：It also discusses potential therapies for AD based on peptides that target various aspects of the disease's pathogenesis.
局限
未能获取全文，具体设计细节、失访与统计学处理无法核验。摘要为截断文本，下游结论不完整。
对本项目的价值
★★☆☆☆ 脑老化是最大未满足需求，也是终点最难量化的领域；biomarker 与认知读数选择最敏感。
原文题录
- 英文标题：[Prospects of application of peptide preparations in therapy of Alzheimer's disease.].
- 期刊与标识：Adv Gerontol · PMID 42935328 · DOI 10.34922/AE.2026.39.4.002**
C 级证据分级：C 级（预印本 / 观点评论，非原始研究）
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