时间标签:数据日期 2026-11-05 · 生成时间 2026-11-05 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 | 情报发生日期 2026-11-05
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摘要(PubMed 原文节选)
Wet granulation is an interfacial reconstruction process mediated by liquid binders. However, the mechanisms underlying the distinct granulation behaviors of drugs with different solubilities remain poorly understood due to a lack of molecular-level insight. Here, we elucidate these mechanisms using density functional theory (DFT) calcula…
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原文题录
- 中文题名:不同溶解度药物湿法制粒机制的分子洞见
- 英文标题:Molecular Insights into the Wet Granulation Mechanisms of Drugs with Different Solubilities.
- 期刊与标识:Molecular pharmaceutics · PMID 42969744 · DOI 10.1021/acs.molpharmaceut.6c00831