时间标签：数据日期 2026-11-01 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31–2026/11/01 ｜ 情报发生日期 2026-11-01
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
This study aimed to evaluate the prognostic value of a composite score integrating the neutrophil-to-lymphocyte ratio (NLR), serum albumin, and D-dimer levels for predicting 1-year mortality in geriatric patients with proximal femur…
方法
This retrospective cohort study included 300 patients aged ≥ 65 years who were admitted with proximal femur fractures and underwent surgical treatment between November 2023 and March 2026.；An exploratory unweighted 0-3 composite score was constructed from cohort-derived ROC thresholds for NLR, albumin, and D-dimer.；Addition of the score to the basic clinical model yielded a category-free NRI of 0.27 (95% CI: 0.14-0.40; p < 0.001) and an IDI of 0.068 (95% CI: 0.035-0.101; p < 0.001), indicating improved apparent risk separation within the derivation…
核心结论
Non-survivors were older and had significantly higher NLR and D-dimer levels and lower albumin levels (all p < 0.001).；In mutually exclusive adjusted regression models, higher NLR and D-dimer levels, lower albumin levels, and a higher composite score were associated with 1-year mortality.；In the composite-score model, each 1-point increase in score was associated with mortality after adjustment for clinical covariates (adjusted OR: 2.82, 95% CI: 1.95-4.08; p < 0.001).；In this retrospective single-center cohort, the composite score integrating NLR, albumin, and D-dimer was associated with 1-year mortality and showed promising apparent discriminatory performance.
局限
（原文未给出可直接抽取的对应表述）
对本项目的价值
人群纵向证据，可用于假说生成与终点选择：线粒体是衰老干预的共同下游效应器，可用于跨器官效应的统一读数。 ｜ 价值分 1.0/5（★☆☆☆☆）
全文来源
未取到全文 → 本卡为摘要级解读，未核验全文
原文题录
- 英文标题：A composite inflammation-nutrition-coagulation score and 1-year mortality in geriatric proximal femur fractures: a retrospective cohort study.
- 期刊与标识：Archives of orthopaedic and trauma surgery · PMID 42963489 · DOI 10.1007/s00402-026-06512-z
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。