数据日期 2026-10-29 · 生成时间 2026-10-29 06:03
研究问题
Acute pulmonary embolism (PE) is a common and potentially fatal cardiovascular condition [1].
方法
Available fields include patient and hospital characteristics, diagnosis and procedure codes, length of stay, hospital charges, and discharge status.;Records carrying only chronic or prior-history PE codes were not included.;The NIS does not provide diagnosis-level present-on-admission indicators, and patients cannot be linked across admissions.;Baseline Variables] Patient and hospital characteristics included age, sex, race, weekend admission, payer, household income by ZIP code, hospital region, teaching status, and hospital bed size.
核心结论
Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) were reported.;Of these, 67.1% were classified as low HFRS, 31.5% as intermediate HFRS, and 1.5% as high HFRS.;Women accounted for 50.0%, 55.2%, and 58.4% of the three groups, respectively. ‖ 结论:Prospective validation is needed before it is used for treatment decisions or as an additional prognostic tool in acute PE.
局限
The weaker associations after excluding acute-prone components suggest that this limitation affected the estimates.;Finally, the exploratory discrimination analysis does not establish calibration, clinical benefit, or added value beyond validated PE risk tools.
对本项目的价值
★★☆☆☆ 方法学进展决定我们能否在有限样本下检出真实效应,属基础设施级收益。设计 问卷。
全文来源
PMC JATS 全文(正文 19,237 字符,已过标题/DOI 逐字归属校验)
原文题录
- 英文标题:Frailty Impact on In-Hospital Outcomes Among Patients Hospitalized with Acute Pulmonary Embolism: A National Inpatient Sample Analysis.
- 期刊与标识:J Clin Med · PMID 42941622 · DOI 10.3390/jcm15208107**
A 级证据分级:A 级(同行评议人体研究)
本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。
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