时间标签：数据日期 2026-11-03 · 生成时间 2026-11-03 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 ｜ 情报发生日期 2026-11-03
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摘要（PubMed 原文节选）
BACKGROUND: Diabetes mellitus is a chronic metabolic disorder characterised by hyperglycaemia, dyslipidaemia, hepatic dysfunction, and loss of pancreatic β-cells. Vitamin D3 (D3) may influence glucose and lipid metabolism and has been investigated for its potential complementary effects when administered with metformin (MT). In the present study, the anti-diabetic activity of D3 alone and when combined with MT was evaluated in Streptozotocin (STZ) induced diabetic mice. METHODS: Swiss albino mice were made diabetic using STZ (45 mg/kg) injected intraperitoneally for 3 days. Diabetic mice were treated with MT (250 mg/kg), D3 (100 μg/kg), or MT + D3 for 21 days. The fasting blood glucose, seru…
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原文题录
- 中文题名：二甲双胍与维生素 D3 联合治疗糖尿病的潜力探索
- 英文标题：Exploring the Therapeutic Potential of Metformin and Vitamin D3 Combination in the Management of Diabetes Mellitus.
- 期刊与标识：Endocrinol Diabetes Metab · PMID 42967578 · DOI 10.1002/edm2.70384 · EDAT 2026-11-01