时间标签：数据日期 2026-11-01 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31–2026/11/01 ｜ 情报发生日期 2026-11-01
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
The gut microbiota is considered an important target for the toxicity of environmental phenols, yet the epidemiological evidence elucidating their associations in adults remains limited.
方法
This study investigated associations between phenol exposure and gut microbiota in 241 adults from Shenzhen, China.
核心结论
We found that exposure to environmental phenols was significantly associated with altered gut microbiota diversity, composition and function.；Bisphenol C was negatively associated with α-diversity, whereas benzylparaben and ethylparaben were positively associated with it.；Exposure to methylparaben, triclosan, isopropylparaben and propylparaben was significantly associated with altered gut microbial community structure.；Taxa analysis showed that methylparaben was negatively associated with the relative abundance of two beneficial species, Bacteroides salyersiae and Anaerostipes caccae.
局限
Further prospective investigations are warranted to validate our findings.
对本项目的价值
人群纵向证据，可用于假说生成与终点选择：微生物组是可修饰性最强的干预层，适合做组合与个体化。 ｜ 价值分 1.0/5（★☆☆☆☆）
全文来源
未取到全文 → 本卡为摘要级解读，未核验全文
原文题录
- 英文标题：Associations of environmental phenols exposure with gut microbiota in a general population from Shenzhen, China.
- 期刊与标识：Ecotoxicology and environmental safety · PMID 42962471 · DOI 10.1016/j.ecoenv.2026.120990
B 级证据分级：B 级（同行评议临床前研究，主要为动物模型）
本文核心结论来自动物模型或体外细胞学，属临床前证据，不能外推至人体。「延长健康寿命」「改善功能」等表述在小鼠中的意义，与人类临床结局之间仍有距离。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。