时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
With the continuous increase in the aging population and the number of immunocompromised individuals, invasive fungal infections (IFIs) caused by Candida albicans have become increasingly severe, highlighting an urgent clinical need for novel antifungal agents. Using itraconazole as a lead compound, we employed a scaffold hopping strategy…
对本项目的价值
参考价值：属「衰老机制与老年临床」方向；其他衰老相关栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.5/5（★★☆☆☆）
全文不可及原因
存在 PMCID（PMC13725855）但全文抽取或题名归属校验未通过，按规降级为摘要级
原文题录
- 中文题名：(苯乙炔基)苯氧甲基-1,3-二氧戊环三唑类新型 CYP51 抑制剂的设计、合成与抗真菌活性
- 英文标题：Design, synthesis, and antifungal activity of (phenylethynyl) phenoxymethyl-1,3-dioxolane triazoles as novel CYP51 inhibitors.
- 期刊与标识：RSC medicinal chemistry · PMID 42974394 · DOI 10.1039/d6md00652c · PMC PMC13725855