时间标签:数据日期 2026-11-05 · 生成时间 2026-11-05 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 | 情报发生日期 2026-11-05
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摘要(PubMed 原文节选)
Targeted kinase inhibitors often yield transient or incomplete responses because tumour cells buffer pathway blockade through signalling cross-talk, motivating synergistic drug combinations. However, it remains unclear whether synergy typically arises from engaging new signalling programs or from reinforcing the dominant effects of each m…
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原文题录
- 中文题名:解析激酶抑制剂组合协同性生长抑制的分子机制
- 英文标题:Deciphering molecular mechanisms of synergistic growth reduction in kinase inhibitor combinations.
- 期刊与标识:Molecular & cellular proteomics : MCP · PMID 42971429 · DOI 10.1016/j.mcpro.2026.101700