时间标签：数据日期 2026-10-31 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/28–2026/10/31 ｜ 情报发生日期 2026-10-31
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
Cloacal malformations are rare congenital condition affecting females, characterised by the convergence of the urinary tract, reproductive tract, and rectum into a single channel. Complex medical interventions are often required from the neonatal period onwards, with potential lifelong implications for bowel, urinary, and gynaecological health. Few centres have substantial experience in treatment and long-term support. Research on the lived experience and psychosocial impact of cloacal malformations is limited, particularly during the transition from adolescence to adulthood. This qualitative study explored how young people born with cloacal malformations live with the condition and what their experiences are of past and ongoing treatment.
局限
未能获取全文，具体设计细节、失访与统计学处理无法核验。
对本项目的价值
★☆☆☆☆ 生殖衰老提供「衰老速率可被激素轴调节」的天然实验窗口。
原文题录
- 英文标题：The psychosocial impact of living with cloacal malformations in young people: A qualitative study.
- 期刊与标识：J Pediatr Adolesc Gynecol · PMID 42962848 · DOI 10.1016/j.jpag.2026.10.007
B 级证据分级：B 级（同行评议临床前研究，主要为动物模型）
本文核心结论来自动物模型或体外细胞学，属临床前证据，不能外推至人体。「延长健康寿命」「改善功能」等表述在小鼠中的意义，与人类临床结局之间仍有距离。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。