时间标签：数据日期 2026-11-03 · 生成时间 2026-11-03 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 ｜ 情报发生日期 2026-11-03
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
BACKGROUND: Reduced kidney function affects the levels of many Alzheimer's disease and related dementias (ADRD) blood-based biomarkers (BBMs). The extent to which kidney function is associated with serum levels of brain-derived tau (BD-tau), a novel BBM specific for Alzheimer's disease-type neurodegeneration, is unknown. METHODS: ADRD BBMs were measured in stored serum samples from 443 BRain IN Kidney Disease study participants (mean age 68.9 years, 49% female). RESULTS: Lower estimated glomerular filtration rate (eGFR; poorer kidney function) was inversely associated with levels of serum BD-tau: BD-tau 54.6 pg/mL (standard deviation [SD] 24.47) for eGFR < 15 mL/min/1.73 m2, 34.16 [20.47] fo…
对本项目的价值
中等价值：属「脑老化与认知轨迹」方向；代谢 / 内分泌 / 肝肾老化的界面栏目可用作本项目文献库与综述素材。 ｜ 价值分 2.3/5（★★☆☆☆）
全文不可及原因
标注 OA 但 PDF 下载失败或未通过题名指纹归属校验
原文题录
- 中文题名：慢性肾脏病与阿尔茨海默病血液生物标志物：肾病中的大脑研究
- 英文标题：Chronic kidney disease and blood-based biomarkers of Alzheimer's disease: the brain in kidney disease study.
- 期刊与标识：Alzheimers Dement · PMID 42967588 · DOI 10.1002/alz.71940 · EDAT 2026-11-01