研究进展

丁丙诺啡与全激动剂阿片类药物的跌倒风险比较:未见显著差异

来源:The Senior care pharmacist · PMID 42957994 · DOI 10.4140/tcp.n.2026.226 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-01 期 · 摘要级(file_id dlMXdlgtPZzo,实际下载核验) · 摘要级,未获取付费墙全文

时间标签:数据日期 2026-11-01 · 生成时间 2026-11-01 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31–2026/11/01 | 情报发生日期 2026-11-01

证据级别:摘要级。本条依据 PubMed 结构化摘要与元数据撰写,付费墙全文未获取、未逐节核验,本站未做任何数值推算补全。

研究问题

However, fall risk in patients with buprenorphine has not been directly compared with full agonist opioids or the partial agonist tramadol.;Objective: DrugCompare the proportion of positive fall risk screenings among older adults in a primary care practice prescribed full agonist opioids or tramadol with those prescribed buprenorphine.

方法

Methods: Eligible patients were aged ≥ 65 years and had buprenorphine, tramadol, or full agonist opioid on their active medication list.

核心结论

Results: Fall risk screening positivity did not differ significantly between groups (69% buprenorphine vs 58% other opioids; P = .179).;Conclusion: The proportion of positive fall risk screenings did not differ significantly between older adults taking buprenorphine versus full agonist opioids.

局限

Association between use of opioid products and fall risk among subpopulations warrants further investigation.

对本项目的价值

临床前机制证据,需评估物种外推与剂量可行性:代谢—器官轴是干预安全性的主要约束面。 | 价值分 1.0/5(★☆☆☆☆)

全文来源

未取到全文 → 本卡为摘要级解读,未核验全文

原文题录

  • 英文标题:Comparing Fall Risk in Older Adults on Full Agonist Opioids versus Buprenorphine Therapy.
  • 期刊与标识:The Senior care pharmacist · PMID 42957994 · DOI 10.4140/tcp.n.2026.226

A 级证据分级:A 级(同行评议人体研究)

本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。

关于本文的文献来源:本站依据 IMA 知识库「五刊监控·深度文献卡片」(SOP §4.2 摘要级)撰写,依据期刊公开摘要与 PubMed 元数据;付费墙全文未获取之处已标注「待补全文」,未做任何数值推算补全。