研究进展

2 型慢性鼻窦炎伴鼻息肉术后年龄相关结局与生物制剂治疗需求

来源:Eur Arch Otorhinolaryngol · PMID 42966786 · DOI 10.1007/s00405-026-10774-z · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-03 期 · 摘要级(file_id dGdXdaLpSURA,实际下载核验 387,231 B) · 摘要级,未获取付费墙全文

时间标签:数据日期 2026-11-03 · 生成时间 2026-11-03 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 | 情报发生日期 2026-11-03

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摘要(PubMed 原文节选)

BACKGROUND: CRSwNP driven by type 2 inflammation is common across all ages, yet surgical outcomes in elderly patients remain poorly characterized. This study evaluated the safety and efficacy of ESS in patients aged ≥ 65 years with type 2 CRSwNP and compared outcomes with younger counterparts in the era of biologic therapy. METHODS: A retrospective cohort study was conducted at Tel Aviv Sourasky Medical Center, including 120 patients with type 2 CRSwNP who underwent ESS between January 2021 and December 2023. Patients were stratified into Group 0 (< 65 years, n = 94) and Group 1 (≥ 65 years, n = 26). Primary outcomes included postoperative complication rates and subjective improvement via SN…

对本项目的价值

参考价值:属「免疫衰老 / 炎症衰老」方向;其他衰老相关栏目可用作本项目文献库与综述素材。 | 价值分 1.7/5(★★☆☆☆)

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原文题录

  • 中文题名:2 型慢性鼻窦炎伴鼻息肉术后年龄相关结局与生物制剂治疗需求
  • 英文标题:Age-related outcome and biological treatment need after surgery for chronic rhinosinusitis with nasal polyposis type 2.
  • 期刊与标识:Eur Arch Otorhinolaryngol · PMID 42966786 · DOI 10.1007/s00405-026-10774-z · EDAT 2026-11-01

A 级证据分级:A 级(同行评议人体研究)

本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。

关于本文的文献来源:本站依据 IMA 知识库「五刊监控·深度文献卡片」(SOP §4.2 摘要级)撰写,依据期刊公开摘要与 PubMed 元数据;付费墙全文未获取之处已标注「待补全文」,未做任何数值推算补全。