基础研究

fNIRS 测得的局部自发活动年龄模式:婴儿期更不可预测,儿童期局部重组

来源:Brain Res Bull · PMID 42966412 · DOI 10.1016/j.brainresbull.2026.112193 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-03 期 · 摘要级(file_id dGdXdaLpSURA,实际下载核验 387,231 B) · 摘要级,未获取付费墙全文

时间标签:数据日期 2026-11-03 · 生成时间 2026-11-03 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 | 情报发生日期 2026-11-03

证据级别:摘要级。本条依据 PubMed 结构化摘要与元数据撰写,付费墙全文未获取、未逐节核验,本站未做任何数值推算补全。

摘要(PubMed 原文节选)

The maturation of the brain is typically described at the whole-brain scale, whereas age-related changes in spontaneous activity within local brain regions have received comparatively little attention. Resting-state regional dynamics (RSRD) are defined as the temporal variability characteristics of activity within a single brain region under the resting state, and can stably reflect the intrinsic properties of spontaneous brain activity. The present study compared two age periods: infants (1-8 months of age) recorded during natural sleep and children (4-15 years of age) recorded during wakeful rest, corresponding to distinct developmental stages of rapid postnatal structural and functional b…

对本项目的价值

参考价值:属「衰老机制与老年临床」方向;其他衰老相关栏目可用作本项目文献库与综述素材。 | 价值分 1.7/5(★★☆☆☆)

全文不可及原因

标注 OA 但 PDF 下载失败或未通过题名指纹归属校验

原文题录

  • 中文题名:fNIRS 测得的局部自发活动年龄模式:婴儿期更不可预测,儿童期局部重组
  • 英文标题:Age-related patterns in local spontaneous activity measured by fNIRS: greater unpredictability in infancy, local reorganization in childhood.
  • 期刊与标识:Brain Res Bull · PMID 42966412 · DOI 10.1016/j.brainresbull.2026.112193 · EDAT 2026-10-31

B 级证据分级:B 级(同行评议临床前研究,主要为动物模型)

本文核心结论来自动物模型或体外细胞学,属临床前证据,不能外推至人体。「延长健康寿命」「改善功能」等表述在小鼠中的意义,与人类临床结局之间仍有距离。

关于本文的文献来源:本站依据 IMA 知识库「五刊监控·深度文献卡片」(SOP §4.2 摘要级)撰写,依据期刊公开摘要与 PubMed 元数据;付费墙全文未获取之处已标注「待补全文」,未做任何数值推算补全。