数据日期 2026-10-29 · 生成时间 2026-10-29 06:03
研究问题
Bimanual coordination is the ability to execute coordinated movements with both hands in a spatially and temporally organized manner [1].
方法
This study used a 2 × 2 mixed design, with age group as the between-participant factor and coordination mode as the within-participant factor.；The nonsphericity correction was set to ε = 1.00, as the within-participant factor had only two levels.；The results indicated that a minimum total sample size of 34 participants (i.e., 17 per group) was necessary to achieve a statistical power level of 80%.；To address the uncertainty regarding the actual statistical power, forty-five right-handed adults were recruited from Tianjin, comprising 23 younger adults (10 men; 18–26 years, M = 20.30 years) and 22 older adults (8 men and 14 women; 57–70 years, M = 64.64 years).
核心结论
In the primary cohort (N = 42), the older adults were less accurate overall, F(1, 40) = 9.54, p = 0.004, η2G = 0.156, and accuracy was lower in the anti-phase than in-phase condition, F(1, 40) = 35.96, p < 0.001, η2G = 0.168.；These effects were qualified by an Age Group × Coordination interaction, F(1, 40) = 18.54, p < 0.001, η2G = 0.094, reflecting a larger age-group difference in the anti-phase condition.；Raw RT showed significant effects of Age Group, F(1, 40) = 53.18, p < 0.001, η2G = 0.536, Coordination Mode, F(1, 40) = 198.03, p < 0.001, η2G = 0.393, and their interaction, F(1, 40) = 25.43, p < 0.001, η2G = 0.077. ‖ 结论：The present study identified age-related differences in behavioral performance and electrophysiological responses during a discrete bimanual coordination task.
局限
Although all older participants met the MMSE eligibility criterion, this screening measure alone cannot rule out mild cognitive impairment.；Future studies using response-locked analyses, response-separated windows, or component decomposition are needed to distinguish these contributions.
对本项目的价值
★★☆☆☆ 相关范围内，作为背景与横向对照收录。设计 横断面、定性研究。
全文来源
PMC JATS 全文（正文 52,126 字符，已过标题/DOI 逐字归属校验）
原文题录
- 英文标题：Age-Related Electrophysiological Reorganization During In-Phase and Anti-Phase Bimanual Coordination.
- 期刊与标识：Brain Sci · PMID 42939328 · DOI 10.3390/brainsci16101075**
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
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