时间标签：数据日期 2026-11-01 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31–2026/11/01 ｜ 情报发生日期 2026-11-01
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
We aimed to quantify associations between sarcopenia and T2DM, prediabetes, and diabetes-related complications in adults.；Adults with T2DM have moderately higher odds of sarcopenia than non-diabetic adults, though observational design and heterogeneity limit causal claims.
方法
Associations were consistent across study designs, regions, and muscle-mass assessment methods, with no single study driving results or evidence of funnel-plot asymmetry.；Adults with T2DM have moderately higher odds of sarcopenia than non-diabetic adults, though observational design and heterogeneity limit causal claims.
核心结论
T2DM was associated with higher odds of sarcopenia (pooled OR 1.61, 95 % CI 1.26-2.06), despite substantial heterogeneity and a wide prediction interval.；Associations were consistent across study designs, regions, and muscle-mass assessment methods, with no single study driving results or evidence of funnel-plot asymmetry.；Prediabetes was not significantly associated with sarcopenia (OR 1.16, 95 % CI 0.63-2.15).；Among complications, diabetic foot disease was associated with higher sarcopenia odds, whereas estimates for retinopathy, nephropathy, and neuropathy were imprecise and non-significant.；Adults with T2DM have moderately higher odds of sarcopenia than non-diabetic adults, though observational design and heterogeneity limit causal claims.
局限
Two reviewers independently screened studies, extracted data, and evaluated bias.；T2DM was associated with higher odds of sarcopenia (pooled OR 1.61, 95 % CI 1.26-2.06), despite substantial heterogeneity and a wide prediction interval.；Adults with T2DM have moderately higher odds of sarcopenia than non-diabetic adults, though observational design and heterogeneity limit causal claims.
对本项目的价值
综述级证据，用于快速对齐领域共识与空白：功能结局（衰弱 / 肌少症）是临床转化最可及的终点，适合作为一期终点候选。 ｜ 价值分 1.3/5（★☆☆☆☆）
全文来源
未取到全文 → 本卡为摘要级解读，未核验全文
原文题录
- 英文标题：Association of type 2 diabetes mellitus with sarcopenia in adults: A meta-analysis.
- 期刊与标识：Diabetes research and clinical practice · PMID 42956840 · DOI 10.1016/j.diabres.2026.113619
C 级证据分级：C 级（预印本 / 观点评论，非原始研究）
本文属观点/评论类文献，不是原始研究。其论点依赖于作者对既有证据的梳理与判断，不构成新的实验证据。本站标注 C 级即为此意——阅读时请把它当作「领域内的思考框架」，而非「研究发现」。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。