时间标签：数据日期 2026-11-03 · 生成时间 2026-11-03 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 ｜ 情报发生日期 2026-11-03
研究问题
Conversely, the absence of problems in oral function may indicate the need to investigate other causes.；Although oral function may improve after intervention, whether such improvements prevent physical frailty remains to be tested in the ROK.
方法
Oral frailty is associated with physical frailty, sarcopenia, and mortality; Korean cohort data also link chewing or speaking difficulties with incident frailty. ② What new information is presented?；The Japanese Kashiwa cohort study followed 2,011 adults aged ≥65 years and found that participants with oral frailty, defined as impairment in at least three of six items and observed in 16% of the cohort, subsequently had significantly increased risks of physical frailty, sarcopenia, disability, and mortality by 2.4-, 2.2-, 2.3-, and 2.2-fold, respectively.；Methods This study was conducted as a narrative literature review.
核心结论
The Japanese Kashiwa cohort study followed 2,011 adults aged ≥65 years and found that participants with oral frailty, defined as impairment in at least three of six items and observed in 16% of the cohort, subsequently had significantly increased risks of physical frailty, sarcopenia, disability, and mortality by 2.4-, 2.2-, 2.3-, and 2.2-fold, respectively.；Taken together, the pooled estimates suggest that oral frailty is common among older adults, although prevalence varies substantially by definition and setting.；This follow-up demonstrated its predictive validity, showing that older adults with an OF-5 score of ≥2 had significantly increased risks of physical disability (adjusted HR, 1.40; 95% CI, 1.14–1.72) and mortality (adjusted HR, 1.44; 95% CI, 1.11–1.87) [ 16 ].
局限
However, given the finite availability of care personnel and financial resources, as well as the need to maintain individuals’ ability to perform activities of daily living and their quality of life, a preventive approach that enables the early detection and management of functional decline before care needs arise should be implemented in parallel.；However, discussions of frailty prevention have largely focused on physical function, falls, and declining muscle strength, whereas the pathway through which declining oral function may lead to physical frailty has received comparatively little attention.
对本项目的价值
参考价值：属「衰弱 / 肌少症功能结局」方向；肌肉骨骼 / 衰弱 / 肌少症栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.9/5（★★☆☆☆）
全文来源
PubMed PMC JATS（正文 31,366 字符，题名指纹 0.83，已过 DOI 逐字 + 题名指纹 + 正文长度三重归属校验）
原文题录
- 中文题名：口腔衰弱预防的需求与未来任务
- 英文标题：The Need for Oral Frailty Prevention and Future Tasks.
- 期刊与标识：Public Health Wkly Rep · PMID 42968962 · DOI 10.56786/PHWR.2026.19.41suppl.3 · PMC PMC13724136 · EDAT 2026-11-02