研究进展

帕金森病肌少症分期评估:基于 ICF 框架的 ISarcoPRM 算法

来源:American journal of physical medicine & rehabilitation · PMID 42952010 · DOI 10.1097/phm.0000000000003188 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-01 期 · 摘要级(file_id dlMXdlgtPZzo,实际下载核验) · 摘要级,未获取付费墙全文

时间标签:数据日期 2026-11-01 · 生成时间 2026-11-01 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31–2026/11/01 | 情报发生日期 2026-11-01

证据级别:摘要级。本条依据 PubMed 结构化摘要与元数据撰写,付费墙全文未获取、未逐节核验,本站未做任何数值推算补全。

研究问题

This study aimed to determine sarcopenia status in patients with Parkinson's disease (PD), classified as early-stage (<2.5) and moderate-stage (≥2.5) by the Modified Hoehn and Yahr Scale, and in healthy controls using the ICF-based…

方法

A total of 63 participants were included in this cross-sectional study: 42 patients with PD and 21 healthy controls.;Participants were classified as non-sarcopenic, dynapenic, or sarcopenic according to ISarcoPRM criteria.

核心结论

The prevalence of sarcopenia differed significantly across groups (P=0.016), with higher rates observed in patients with moderate-stage PD.

局限

A total of 63 participants were included in this cross-sectional study: 42 patients with PD and 21 healthy controls.

对本项目的价值

观察性关联,仅用于假说生成,不可作因果:功能结局(衰弱 / 肌少症)是临床转化最可及的终点,适合作为一期终点候选。 | 价值分 1.0/5(★☆☆☆☆)

全文来源

未取到全文 → 本卡为摘要级解读,未核验全文

原文题录

  • 英文标题:Stage-Dependent Sarcopenia Status in Parkinson's Disease: An ICF-Based ISarcoPRM Algorithm.
  • 期刊与标识:American journal of physical medicine & rehabilitation · PMID 42952010 · DOI 10.1097/phm.0000000000003188

A 级证据分级:A 级(同行评议人体研究)

本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。

关于本文的文献来源:本站依据 IMA 知识库「五刊监控·深度文献卡片」(SOP §4.2 摘要级)撰写,依据期刊公开摘要与 PubMed 元数据;付费墙全文未获取之处已标注「待补全文」,未做任何数值推算补全。