时间标签:数据日期 2026-11-05 · 生成时间 2026-11-05 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 | 情报发生日期 2026-11-05
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摘要(PubMed 原文节选)
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy driven by diverse genetic and cytogenetic alterations. Serine protease inhibitor Kazal-type 2 (SPINK2) has been reported to be overexpressed in AML and associated with adverse clinical outcomes; recent studies have implicated SPINK2 in the regulation of leukemic prol…
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原文题录
- 中文题名:SPINK2 敲低抑制 MLL-MLLT3 重排 THP-1 细胞增殖并促进细胞死亡
- 英文标题:SPINK2 knockdown reduces proliferation and promotes cell death in MLL-MLLT3-rearranged THP-1 cells.
- 期刊与标识:Histochemistry and cell biology · PMID 42975681 · DOI 10.1007/s00418-026-02548-9