时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
研究问题
The objective of the current study was to retrospectively explore the relationship between EHF hearing and speech-in-noise performance, and a secondary goal was to analyze cognition and aging alongside EHF hearing sensitivity as predictors of speech-in-noise performance.MethodsDesign and participantsThis was a retrospective re-analysis of laboratory recruited participants.；Based on 1,000 bootstrap resamples, marginal R2 was used to determine the variance unique to each predictor and the variance shared between predictors (Stoffel et al., 2021).The PTASF and PTAEHF values were categorized into 5-dB bins to evaluate whether WIN performance differed from the 6-dB-SNR normative criterion (Wilson, 2011).；Mixed linear models controlling for participant were computed to determine whether the mean WIN threshold of each PTA bin was statistically different from the 6 dB SNR cutoff value for normal speech-in-noise performance on the WIN.
方法
However, at the individual level, EHF hearing thresholds can be quite different in patients with similar, normal SF hearing thresholds, and poor EHF thresholds do not solely occur in populations with poor SF thresholds.；The association between EHF thresholds and cognition yielded varying results dependent on age, but degraded speech-in-noise performance associated with higher EHF thresholds was observed regardless of participant age (Helfer et al., 2024).；Hearing loss has also been cited consistently as a predominant potentially modifiable risk factor for cognitive decline (Livingston et al., 2024; Livingston et al., 2020; Livingston et al., 2017; Loughrey et al., 2018), but these associations have been established strictly in relation to elevation of SF hearing, not inclusive of EHF hearing thresholds.In this study, we present clinically relevant functional and EHF audiometric data to provide a clearer basis for establishing a clinical cutoff value of EHF hearing thresholds.
核心结论
Using a linear mixed effects model with a participant-level random intercept, we found WIN thresholds to be significantly affected by both SLSF and SLEHF (marginal R2 = 0.637).；The authors conclude more research is required to determine clinical relevance of EHF audiometry for older populations.In contrast, other studies have supported the conclusion that there exists a relationship between speech-in-noise performance and EHF thresholds (e.g., Mishra et al., 2022b).；However, a standard presentation level was not recommended, and our data suggest that sensation level can influence WIN performance, making these recommendations perhaps premature and requiring further exploration, potentially involving analysis of a level series to assess various presentation levels (Figure 8).It is possible that the WIN is more sensitive to peripheral compromise and subclinical deficits than other speech-in-noise tests (Wilson et al., 2007), especially in those with conventional normal or near normal hearing sensitivity.
局限
IntroductionGrowing evidence suggests that poorer extended high frequency (EHF) hearing detection thresholds (at frequencies > 8 kHz) are associated with the degree of self-reported hearing loss, warranting clinical inclusion in a standard test battery (Helfer et al., 2024; Motlagh Zadeh et al., 2019).；However, clinical application has been limited in part because the field has yet to reach a universal definition of “normal hearing” in the EHF range, despite discussions in the literature establishing that an EHF cutoff value is feasible and recommended (Rodríguez Valiente et al., 2014; Shahnaz and Ciocca, 2026; Stenklev and Laukli, 2004).Cutoff thresholds for the standard frequency (SF; 0.25–8 kHz) in adults have a complex history and there has been international disagreement on the dividing line.；Guidelines were once derived from standards produced by the International Organization for Standardization (ISO); however, for economic reasons, cutoff values were ultimately shifted upwards in the United States to limit the percentage of the population determined to have a hearing impairment (Gatlin and Dhar, 2021).
对本项目的价值
中等价值：属「脑老化与神经退行」方向；脑老化 / 神经退行 / 认知栏目可用作本项目文献库与综述素材。 ｜ 价值分 2.9/5（★★★☆☆）
全文来源
PubMed PMC JATS（正文 47,335 字符，题名指纹 0.91，已过 PubMed PMCID 官方关联 + 题名指纹 + 正文长度归属校验）
原文题录
- 中文题名：扩展高频听力、认知与噪声中言语表现的关系
- 英文标题：Relationships between extended high frequency hearing, cognition, and speech-in-noise performance.
- 期刊与标识：Frontiers in neuroscience · PMID 42978616 · DOI 10.3389/fnins.2026.1933436 · PMC PMC13727533