时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
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摘要（PubMed 原文节选）
Brain aging is a spatially heterogeneous and multi-layered process, yet how protein abundance and post-translational modifications (PTMs) are coordinated across brain regions and over time remains incompletely understood. Here, we present a brain-region-resolved, multi-layer proteomics atlas of mouse brain aging, integrating the proteome,…
对本项目的价值
参考价值：属「衰老细胞清除 / SASP 轴」方向；细胞衰老 / senolytics / SASP栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.8/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名：区域分辨多层蛋白组揭示小鼠脑衰老中以蛋白稳态为中心的翻译后修饰重塑
- 英文标题：Region-resolved multi-layer proteomics reveals proteostasis-centered post-translational remodeling during mouse brain aging.
- 期刊与标识：Molecular & cellular proteomics : MCP · PMID 42977261 · DOI 10.1016/j.mcpro.2026.101701