数据日期 2026-10-29 · 生成时间 2026-10-29 06:03
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
研究问题
Partial edentia (partial absence of teeth) is the most common dental condition, occurring in all age groups, including young and middle-aged patients.
方法
This article, based on an analysis of domestic and international data, demonstrates that dental health is an integral part of overall health, and dental status is inextricably linked to quality of life, requiring a comprehensive approach to the care of these patients.；A systematic review of clinical studies demonstrates that a significant proportion of patients with partial edentia remain without prosthetic replacement for extended periods of time, resulting in the development of functional impairments that accelerate systemic involutional processes.；The aim of this article is to use scientific literature to define a clinical profile of a patient with partial edentia in terms of premature…
核心结论
A systematic review of clinical studies demonstrates that a significant proportion of patients with partial edentia remain without prosthetic replacement for extended periods of time, resulting in the development of functional impairments that accelerate systemic involutional processes.；To study partial edentia from the perspective of accelerated aging, it is appropriate to use the concept of intrinsic vitality, considering dental health as a component of the somatic domain that influences nutritional status, muscle function, and cognitive health.；Functional impairments associated with partial edentia are accompanied by aesthetic changes, which often lead to psychological and social problems.；Therefore, in the context of premature aging, partial edentia can be considered a pathogenetically significant biomarker of systemic aging. ‖ 结论：Therefore, in the context of premature aging, partial edentia can be considered a pathogenetically significant biomarker of systemic aging.
局限
未能获取全文，具体设计细节、失访与统计学处理无法核验。
对本项目的价值
★★☆☆☆ 脑老化是最大未满足需求，也是终点最难量化的领域；biomarker 与认知读数选择最敏感。
原文题录
- 英文标题：[Clinical phenotype of the patient with partial adentia in longevity medicine.].
- 期刊与标识：Adv Gerontol · PMID 42935337 · DOI 10.34922/AE.2026.39.4.011**
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」（SOP §4.2 摘要级）撰写，依据期刊公开摘要与 PubMed 元数据；付费墙全文未获取之处已标注「待补全文」，未做任何数值推算补全。