时间标签:数据日期 2026-11-05 · 生成时间 2026-11-05 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 | 情报发生日期 2026-11-05
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摘要(PubMed 原文节选)
Anaplastic thyroid carcinoma (ATC) is rare but highly aggressive with a median survival of only four months post-diagnosis. Current treatments offer limited survival benefits, highlighting the urgent need for novel targeted therapies. One of the hallmarks of ATC is the dysregulation of key signaling cascades, particularly the PI3K/AKT/mTO…
对本项目的价值
参考价值:属「营养感知—自噬—蛋白稳态轴」方向;mTOR / 自噬 / 蛋白质稳态栏目可用作本项目文献库与综述素材。 | 价值分 1.8/5(★★☆☆☆)
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名:PIP3 与 EGFR 双靶向多肽复合物药物的开发:面向未分化型甲状腺癌的特异性递送与治疗
- 英文标题:PIP3 and EGFR Dual Targeting for the Development of a Polypeptide Complex Drug Aimed at the Specific Delivery and Therapy of Anaplastic Thyroid Carcinoma.
- 期刊与标识:Molecular pharmaceutics · PMID 42969702 · DOI 10.1021/acs.molpharmaceut.6c00569