研究进展

神经退行疾病新型睡眠分期方法:晚期帕金森病的可行性与可靠性

来源:Sleep Med · PMID 42967379 · DOI 10.1016/j.sleep.2026.109334 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-03 期 · 摘要级(file_id dGdXdaLpSURA,实际下载核验 387,231 B) · 摘要级,未获取付费墙全文

时间标签:数据日期 2026-11-03 · 生成时间 2026-11-03 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 | 情报发生日期 2026-11-03

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摘要(PubMed 原文节选)

INTRODUCTION: In neurodegenerative diseases, damage to sleep-wake regulating brain regions alters sleep architecture (e.g., loss of spindles and K-complexes, EEG slowing during wakefulness and REM sleep), challenging the current American Academy of Sleep Medicine (AASM) rules for scoring sleep. In Parkinson disease (PD) patients, we assessed the feasibility and interrater reliability of a previously described novel sleep scoring methodology. METHODS: Video-polysomnography of 15 PD patients and five age-matched controls were scored blinded by five trained raters (two neurologists and three technicians) with different levels of expertise. Recordings were first scored empirically following the …

对本项目的价值

参考价值:属「脑老化与认知轨迹」方向;脑老化 / 神经退行 / 认知栏目可用作本项目文献库与综述素材。 | 价值分 1.5/5(★★☆☆☆)

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原文题录

  • 中文题名:神经退行疾病新型睡眠分期方法:晚期帕金森病的可行性与可靠性
  • 英文标题:Novel sleep scoring method for neurodegenerative diseases: feasibility and reliability in advanced Parkinson disease.
  • 期刊与标识:Sleep Med · PMID 42967379 · DOI 10.1016/j.sleep.2026.109334 · EDAT 2026-11-01

A 级证据分级:A 级(同行评议人体研究)

本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。

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