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干预脂肪细胞衰老:脂质前药作为代谢病治疗的新兴策略

来源:Curr Med Sci · PMID 42965765 · DOI 10.1007/s11596-026-00251-3 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-03 期 · 摘要级(file_id dGdXdaLpSURA,实际下载核验 387,231 B) · 摘要级,未获取付费墙全文

时间标签:数据日期 2026-11-03 · 生成时间 2026-11-03 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 | 情报发生日期 2026-11-03

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摘要(PubMed 原文节选)

The accelerating aging of the global population has made aging and its related diseases major public health challenges in the 21st century. Adipose tissue is not only an energy reservoir but also a crucial endocrine organ and metabolic regulator. Its dysfunction is closely linked to aging and the development of multiple diseases. This review outlines the key characteristics of adipocyte senescence and discusses its pathological contributions to obesity, type 2 diabetes, metabolic dysfunction-associated steatotic liver disease, and cardiovascular diseases. It also summarizes current intervention strategies for adipocyte senescence, including senolytics, senomorphics, caloric restriction, phys…

对本项目的价值

中等价值:属「衰老细胞清除 / SASP 轴」方向;代谢 / 内分泌 / 肝肾老化的界面栏目可用作本项目文献库与综述素材。 | 价值分 2.2/5(★★☆☆☆)

全文不可及原因

无 PMCID 且 OpenAlex / Unpaywall 未提供可下载 OA PDF

原文题录

  • 中文题名:干预脂肪细胞衰老:脂质前药作为代谢病治疗的新兴策略
  • 英文标题:Intervening in Adipocyte Senescence: Lipid Prodrugs as an Emerging Strategy for Metabolic Disease Treatment.
  • 期刊与标识:Curr Med Sci · PMID 42965765 · DOI 10.1007/s11596-026-00251-3 · EDAT 2026-10-31

C 级证据分级:C 级(预印本 / 观点评论,非原始研究)

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