时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
Age-related decline in male fertility, including diminished sperm quality, poses significant risks to offspring health and is exacerbated by modern trends toward delayed parenthood. Focusing on the hypothalamus-pituitary-testis axis, which governs hormonal control of male reproduction, we identified Synage, a long noncoding RNA expressed …
对本项目的价值
参考价值：属「脑老化与神经退行」方向；脑老化 / 神经退行 / 认知栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.5/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名：下丘脑 lncRNA Synage 经抑制 GnRH 神经元 A 型钾电流预防年龄相关精子质量下降
- 英文标题：Hypothalamic lncRNA Synage prevents age-related sperm quality decline by suppressing A-type potassium currents in GnRH neurons.
- 期刊与标识：Proceedings of the National Academy of Sciences of the United States of America · PMID 42975938 · DOI 10.1073/pnas.2612408123