时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
Hexafluoropropylene oxide dimer acid (HFPO-DA, also known as GenX) is an emerging per- and polyfluoroalkyl substance (PFAS) alternative increasingly detected in the environment, raising concerns about its potential long-term health effects. Neuronal senescence is a critical hallmark of brain aging and has been implicated in age-related ne…
对本项目的价值
参考价值：属「衰老细胞清除 / SASP 轴」方向；细胞衰老 / senolytics / SASP栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.8/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名：与人体相关六氟环氧丙烷二聚酸暴露经 KDM6A 介导 CDC42 K27 去甲基化驱动神经元衰老
- 英文标题：Human-relevant hexafluoropropylene oxide dimer acid exposure drives neuronal senescence via KDM6A-mediated CDC42 K27 demethylation.
- 期刊与标识：Journal of hazardous materials · PMID 42970922 · DOI 10.1016/j.jhazmat.2026.144095