时间标签：数据日期 2026-11-01 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31–2026/11/01 ｜ 情报发生日期 2026-11-01
研究问题
Elderly HF patients usually have a poorer prognosis due to comorbidities and physiological decline [ ].；Heart failure with preserved ejection fraction (HFpEF) is the most prevalent phenotype among elderly patients, characterized by left ventricular ejection fraction ≥ 50%, typical signs and/or symptoms of HF, and
方法
All participants were uniformly diagnosed with HFpEF in accordance with the 2023 ESC Guidelines [ ].
核心结论
Survival analysis of different groups of patients under CONUT score and GNRI score For CONUT scores, higher scores were linked to increased all-cause mortality risk and decreased survival probability, and for GNRI scores, lower scores were associated with…；As the CONUT scores increased, the rates of all-cause death, cardiovascular death, all-cause readmission, and HF-related readmission rose significantly (P < 0.05).；By contrast, GNRI score was independently associated with lower mortality, indicating that better nutritional status correlated with reduced death risk.；Accumulating evidence suggests that malnutrition is associated with adverse outcomes in HF patients, potentially through its effects on myocardial energy metabolism and immune function [ , , ].
局限
Future prospective, multicenter studies with larger sample sizes and comprehensive multivariable adjustment are warranted to validate the prognostic value of CONUT and GNRI in elderly HFpEF patients.；This observation may reflect the known heterogeneity of HFpEF, but our cross-sectional data cannot determine whether nutritional status is directly associated with cardiac remodeling.
对本项目的价值
人群纵向证据，可用于假说生成与终点选择：炎症衰老是多数慢病共病的上游枢纽，可用于分层与联合干预设计。 ｜ 价值分 1.0/5（★☆☆☆☆）
全文来源
PubMed PMC JATS 全文（正文 22,219 字符，已过 DOI 逐字 + 题名指纹双重归属校验）
原文题录
- 英文标题：Prognostic Value of the Geriatric Nutritional Risk Index and Controlling Nutritional Status Score in Patients Aged ≥ 75 Years With Heart Failure With Preserved Ejection Fraction.
- 期刊与标识：Cardiology research · PMID 42964223 · DOI 10.14740/cr2282
A 级证据分级：A 级（同行评议人体研究）
本文属人体研究证据，但需注意：观察性或小样本干预的结论不等于已证实临床获益；效应量与长期安全性仍需更大规模、更长随访的试验验证。
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