时间标签:数据日期 2026-11-01 · 生成时间 2026-11-01 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31–2026/11/01 | 情报发生日期 2026-11-01
证据级别:摘要级。本条依据 PubMed 结构化摘要与元数据撰写,付费墙全文未获取、未逐节核验,本站未做任何数值推算补全。
研究问题
The purpose of this exploratory study was to identify the relative contributions of affective, cognitive, fatigue-related, balance, and motor factors associated with FFAB in individuals with early-stage PD and to generate hypotheses for…;These exploratory findings identify affective and physical factors as promising targets for research aimed at understanding FFAB.
方法
A cross-sectional secondary analysis was conducted in mild to moderate PD (Hoehn and Yahr stages 1-3, n = 35).
核心结论
Fear of falling (FoF) avoidance behavior (FFAB) is common in Parkinson disease (PD) and contributes to reduced activity, deconditioning, and functional decline.;The purpose of this exploratory study was to identify the relative contributions of affective, cognitive, fatigue-related, balance, and motor factors associated with FFAB in individuals with early-stage PD and to generate hypotheses for future investigation.;FFAB in early-stage PD appears strongly associated with depressive symptoms and balance impairment, with modest contributions from motor severity.
局限
A cross-sectional secondary analysis was conducted in mild to moderate PD (Hoehn and Yahr stages 1-3, n = 35).
对本项目的价值
观察性关联,仅用于假说生成,不可作因果:神经退行是长寿干预最难攻的终点,本文提供机制或生物标志物层面的抓手。 | 价值分 1.0/5(★☆☆☆☆)
全文来源
未取到全文 → 本卡为摘要级解读,未核验全文
原文题录
- 英文标题:Exploring Contributors to Fear-Based Activity Avoidance in Parkinson Disease: A Cross-Sectional Analysis of Depression, Balance, and Disease Severity.
- 期刊与标识:Journal of neurologic physical therapy : JNPT · PMID 42954913 · DOI 10.1097/npt.0000000000000588
A 级证据分级:A 级(同行评议人体研究)
本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。
关于本文的文献来源:本站依据 IMA 知识库「五刊监控·深度文献卡片」(SOP §4.2 摘要级)撰写,依据期刊公开摘要与 PubMed 元数据;付费墙全文未获取之处已标注「待补全文」,未做任何数值推算补全。