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酿酒酵母 CNCM I-3856 与维生素 K2 对骨质疏松患者肠道菌群的影响

来源:Food Res Int · PMID 42967716 · DOI 10.1016/j.foodres.2026.120894 · 来源:IMA 知识库《文献层·文献监控卡片》2026-11-03 期 · 摘要级(file_id dGdXdaLpSURA,实际下载核验 387,231 B) · 摘要级,未获取付费墙全文

时间标签:数据日期 2026-11-03 · 生成时间 2026-11-03 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 | 情报发生日期 2026-11-03

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摘要(PubMed 原文节选)

The gut microbiome may be involved in bone health through the gut-bone axis. Saccharomyces cerevisiae CNCM I-3856 benefits gut health in patients with irritable bowel syndrome, which is more prevalent in women and may be associated with higher osteoporosis prevalence. We evaluated the effects of S. cerevisiae CNCM I-3856 ± vitamin K2 (K2) on the gut microbiota of patients with osteoporosis and healthy controls. Short-term in vitro colonic fermentations were performed using feces from healthy and osteoporosis-diagnosed individuals (n = 12/cohort). Three conditions were tested: untreated, probiotic, probiotic+K2. Colonic supernatants (48 h) were evaluated for microbial metabolic and community …

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原文题录

  • 中文题名:酿酒酵母 CNCM I-3856 与维生素 K2 对骨质疏松患者肠道菌群的影响
  • 英文标题:Effects of Saccharomyces cerevisiae CNCM I-3856 and vitamin K2 on the gut microbiota of patients with osteoporosis and healthy controls using in vitro short-term colonic simulations.
  • 期刊与标识:Food Res Int · PMID 42967716 · DOI 10.1016/j.foodres.2026.120894 · EDAT 2026-11-01

A 级证据分级:A 级(同行评议人体研究)

本文属人体研究证据,但需注意:观察性或小样本干预的结论不等于已证实临床获益;效应量与长期安全性仍需更大规模、更长随访的试验验证。

关于本文的文献来源:本站依据 IMA 知识库「五刊监控·深度文献卡片」(SOP §4.2 摘要级)撰写,依据期刊公开摘要与 PubMed 元数据;付费墙全文未获取之处已标注「待补全文」,未做任何数值推算补全。