时间标签:数据日期 2026-11-05 · 生成时间 2026-11-05 05:30(Asia/Shanghai)| 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 | 情报发生日期 2026-11-05
证据级别:摘要级。本条依据 PubMed 结构化摘要与元数据撰写,付费墙全文未获取、未逐节核验,本站未做任何数值推算补全。
摘要(PubMed 原文节选)
DNA double-strand breaks (DSBs) are the most genotoxic form of DNA damage. Unrepaired DSBs may cause loss of chromosome fragments at mitosis, while incorrectly repaired DSBs can cause chromosome aberrations and other adverse effects, leading to cell cycle arrest, senescence, cell death, or neoplastic transformation. Detecting and quantify…
对本项目的价值
参考价值:属「衰老细胞清除 / SASP 轴」方向;细胞衰老 / senolytics / SASP栏目可用作本项目文献库与综述素材。 | 价值分 1.8/5(★★☆☆☆)
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名:基因组与成像方法检测和定量 DNA 双链断裂:能力与局限的批判性评估
- 英文标题:Detection and quantification of DNA double-strand breaks by genomic and imaging methods: a critical appraisal of capabilities and limitations.
- 期刊与标识:Nucleic acids research · PMID 42979755 · DOI 10.1093/nar/gkag1035