时间标签：数据日期 2026-11-03 · 生成时间 2026-11-03 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 ｜ 情报发生日期 2026-11-03
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
BACKGROUND: Post-traumatic stress disorder (PTSD) may accelerate biological aging, but the pathways and evidence remain uncertain. We systematically reviewed associations between PTSD and epigenetic and other aging biomarkers. METHODS: We searched PubMed, Embase, Web of Science, and Scopus through 1 March 2026 for studies of adults with validated PTSD assessment. Two reviewers screened records and extracted data. Risk of bias was assessed with the Newcastle-Ottawa Scale. Findings were synthesized narratively because study designs and outcomes were heterogeneous. RESULTS: Twenty-four studies including 512,768 participants met the inclusion criteria. Twenty-two (91.7%) reported positive associ…
对本项目的价值
中高价值：属「表观遗传时钟与生物学年龄读数」方向；其他衰老相关栏目可用作本项目文献库与综述素材。 ｜ 价值分 3.0/5（★★★☆☆）
全文不可及原因
无 PMCID 且 OpenAlex / Unpaywall 未提供可下载 OA PDF
原文题录
- 中文题名：连接 PTSD 与加速衰老的生物学与表观遗传通路：系统综述与叙述性整合
- 英文标题：Biological and epigenetic pathways linking PTSD to accelerated aging: a systematic review and narrative synthesis.
- 期刊与标识：Epigenomics · PMID 42968558 · DOI 10.1080/17501911.2026.2751831 · EDAT 2026-11-02