时间标签：数据日期 2026-10-31 · 生成时间 2026-11-01 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/28–2026/10/31 ｜ 情报发生日期 2026-10-31
研究问题
However, stroke in younger adults need special attention because it causes long-term disability and loss of productivity during working years of life.；Research gaps are still present in the current understanding of stroke epidemiology in India.；However, relatively few studies have explicitly quantified the relative contributions of population growth, population ageing, and epidemiological change to the increase in absolute stroke burden.
方法
Data processing and quality-control procedures were completed prior to statistical analysis.；For ischemic stroke, ICH, and SAH, we analysed each subtype using ASRs to highlight differences in epidemiological patterns between ischemic and hemorrhagic strokes.；Data were imported from the GBD Results Tool into R version 4.6.1 (R Foundation for Statistical Computing, Vienna, Austria) for preprocessing and statistical analysis.；We used the R packages 'dplyr', 'purrr', and 'sf' for data processing and filtering, and 'ggplot2', 'ggsci', 'ggrepel', 'patchwork', and 'ggbrace' for visualization.
核心结论
From 1990 to 2023, the total burden of stroke in India has increased.；Stroke deaths also increased during this time, rising from 416,863 to 1.03 million (a rise of 148.2%), and DALYs moved from 12.41 million to 25.99 million (an increase of 109.4%) (Table ).；Even though the total burden had increased, the age-standardized trends were very different. ‖ 结论：Overall, the findings highlight that declining standardized rates alone should not be interpreted as a reduction in the public health challenge posed by stroke; demographic change must remain central to future stroke prevention, service planning, and resource allocation in India.
局限
Third, substantial heterogeneity was observed between states, with the geographical distribution of incidence differing from that of death and DALYs.；Deaths and DALYs suggest improving outcomes, but residual disability remains substantial.；One of the most policy-relevant findings was the pronounced geographical heterogeneity in stroke burden.
对本项目的价值
★☆☆☆☆ 血管老化提供可影像量化、可短期读取的中间终点，适合做机制到临床的桥接。最大样本量约 79,584。
全文来源
PMC JATS 全文（正文 46,029 字符，已过标题/DOI 逐字归属校验）
原文题录
- 英文标题：Temporal Trends and Demographic Contributions to Stroke Burden in India, 1990-2023: An Analysis of Global Burden of Disease 2023 Estimates Using Shapley Decomposition and Joinpoint Regression.
- 期刊与标识：Cureus · PMID 42953462 · DOI 10.7759/cureus.117056
B 级证据分级：B 级（同行评议临床前研究，主要为动物模型）
本文核心结论来自动物模型或体外细胞学，属临床前证据，不能外推至人体。「延长健康寿命」「改善功能」等表述在小鼠中的意义，与人类临床结局之间仍有距离。
关于本文的文献来源：本站依据 IMA 知识库「五刊监控·深度文献卡片」撰写，依据已获取的期刊全文（方法、样本量与结论已回到原文核对）；未能获取全文的同批条目另行标注「摘要级」，全程未做任何数值推算补全。