时间标签：数据日期 2026-11-05 · 生成时间 2026-11-05 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/11/02 – 2026/11/06 ｜ 情报发生日期 2026-11-05
证据级别：摘要级。本条依据 PubMed 结构化摘要与元数据撰写，付费墙全文未获取、未逐节核验，本站未做任何数值推算补全。
摘要（PubMed 原文节选）
Protein homeostasis, or proteostasis, ensures a properly folded and functional proteome and is essential for cell survival. Proteins often misfold during stress or because of mutations that alter their structure. Proteostasis assembles misfolded proteins into membrane-less protein quality control (PQC) compartments. Many proteins, includi…
对本项目的价值
参考价值：属「营养感知—自噬—蛋白稳态轴」方向；mTOR / 自噬 / 蛋白质稳态栏目可用作本项目文献库与综述素材。 ｜ 价值分 1.8/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 Europe PMC / OpenAlex / Unpaywall 未提供可下载 OA 全文
原文题录
- 中文题名：Sti1 需要 Hsp70 相互作用区域将错误折叠蛋白沉积于核-液泡连接处
- 英文标题：Sti1 requires its Hsp70-interacting regions to deposit misfolded proteins at the nucleus-vacuole junction.
- 期刊与标识：The Journal of biological chemistry · PMID 42971327 · DOI 10.1016/j.jbc.2026.113712