时间标签：数据日期 2026-11-03 · 生成时间 2026-11-03 05:30（Asia/Shanghai）｜ 检索窗口 PubMed edat 2026/10/31 – 2026/11/03 ｜ 情报发生日期 2026-11-03
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摘要（PubMed 原文节选）
With nearly two-thirds of the UK population living with overweight or obesity, there is an urgent necessity for evidence-based public health guidance to promote a healthy weight. Current weight management advice centres on lifestyle modification. However, existing dieting recommendations fail to consider sex or age. This is a surprising oversight, as it is well established that health outcomes vary significantly between men and women across the lifespan. Our preliminary work in mice and humans suggests young females are more resistant than males to calorie-restriction (CR)-induced fat loss and reductions in energy expenditure, and that this resistance diminishes in older, post-menopausal par…
对本项目的价值
中等价值：属「干预策略与临床转化」方向；干预策略与临床试验栏目可用作本项目文献库与综述素材。 ｜ 价值分 2.2/5（★★☆☆☆）
全文不可及原因
无 PMCID 且 OpenAlex / Unpaywall 未提供可下载 OA PDF
原文题录
- 中文题名：性激素调节热量限制的年龄与性别依赖获益：GendAge 减重研究方案
- 英文标题：Sex Hormones as Regulators of the Age- and Sex-Dependent Benefits of Caloric Restriction: An Emerging Research Protocol of a Controlled Dietary Intervention (The GendAge Weight Loss Study).
- 期刊与标识：Nutr Bull · PMID 42969100 · DOI 10.1111/nbu.70077 · EDAT 2026-11-02